Is There a Renaissance of Glucocorticoids in Rheumatoid Arthritis?

被引：9

作者：

Kirwan, J. R. ^{[1
,2
]}

Gunasekera, W. M. A. ^{[3
]}

机构：

[1] Univ Bristol, Bristol, Avon, England

[2] Univ West England, Acad Rheumatol Unit, Bristol Royal Infirm, Bristol, Avon, England

[3] Peterborough & Stamford NHS Fdn Trust, Peterborough City Hosp, Dept Rheumatol, Edith Cavell Campus, Peterborough, Cambs, England

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2017年 / 102卷 / 04期

关键词：

D O I：

10.1002/cpt.753

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The first therapeutic use of glucocorticoids was in a patient with severe rheumatoid arthritis and the symptomatic benefit was astounding. Adverse effects from increasingly large doses led to them being overshadowed, dismissed as inappropriate treatment, and ignored for 20 years - but in the last 2 decades, the accumulating evidence and clinical practice suggest there is a justified renaissance in their use as a first-line treatment.

引用

页码：574 / 577

页数：4

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