Thermodynamic relations for DNA phase transitions

被引:7
|
作者
Sadhukhan, P. [1 ]
Bhattacharjee, S. M. [2 ]
机构
[1] Univ Gottingen, Inst Theoret Phys, D-37077 Gottingen, Germany
[2] Inst Phys, Bhubaneswar 751005, Orissa, India
关键词
DNA unzipping; Melting and force induced transitions; Thermodynamic relations; LOW-TEMPERATURE; B-DNA; POLYMER; STABILITY; PRESSURE; FORCE; HELIX;
D O I
10.1007/s12648-014-0489-3
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The force induced unzipping transition of a double stranded DNA is considered from a purely thermodynamic point of view. This analysis provides us with a set of relations that can be used to test microscopic theories and experiments. The thermodynamic approach is based on the hypothesis of impenetrability of the force in the zipped state. The melting and the unzipping transitions are considered in the same framework and compared with the existing statistical model results. The analysis is then extended to a possible continuous unzipping transition.
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页码:895 / 904
页数:10
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