Chlorodifluoromethyl phenyl sulfone:: a novel non-ozone-depleting substance-based difluorocarbene reagent for O- and N-difluoromethylations

被引：92

作者：

Zheng, Ji

Li, Ya

Zhang, Laijun

Hu, Jinbo

Meuzelaar, Gerrit Joost

Federsel, Hans-Juergen

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China

[2] AstraZeneca, Global Proc R&D, S-15185 Sodertalje, Sweden

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 48期

关键词：

D O I：

10.1039/b713156a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chlorodifluoromethyl phenyl sulfone, a previously unknown compound that can be readily prepared from non-ODS-based precursors, was found to act as a robust difluorocarbene reagent for O- and N-difluoromethylations.

引用

页码：5149 / 5151

页数：3