miRNAs in Lung Development and Diseases

被引：37

作者：

Boateng, Eistine ^{[1
]}

Krauss-Etschmann, Susanne ^{[1
,2
]}

机构：

[1] German Ctr Lung Res DZL, Leibniz Lung Ctr, Early Life Origins Chron Lung Dis, Res Ctr Borstel, D-23845 Borstel, Germany

[2] Christian Albrechts Univ Kiel, Inst Expt Med, D-24118 Kiel, Germany

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2020年 / 21卷 / 08期

关键词：

lung development; lung diseases; miRNA; human; mouse; PULMONARY ARTERIAL-HYPERTENSION; BRONCHIAL EPITHELIAL-CELLS; NF-KAPPA-B; STEM-CELLS; FIBROSIS; DIFFERENTIATION; EXPRESSION; BETA; PROLIFERATION; MICRORNAS;

D O I：

10.3390/ijms21082765

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The development of the lung involves a diverse group of molecules that regulate cellular processes, organ formation, and maturation. The various stages of lung development are marked by accumulation of small RNAs that promote or repress underlying mechanisms, depending on the physiological environment in utero and postnatally. To some extent, the pathogenesis of various lung diseases is regulated by small RNAs. In this review, we discussed miRNAs regulation of lung development and diseases, that is, COPD, asthma, pulmonary fibrosis, and pulmonary arterial hypertension, and also highlighted possible connotations for human lung health.

引用

页数：16

共 50 条

[1] The roles of exosomal miRNAs and lncRNAs in lung diseases
Yang Li
Zhengrong Yin
Jinshuo Fan
Siyu Zhang
Weibing Yang
Signal Transduction and Targeted Therapy, 4
[2] The roles of exosomal miRNAs and lncRNAs in lung diseases
Li, Yang
Yin, Zhengrong
Fan, Jinshuo
Zhang, Siyu
Yang, Weibing
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2019, 4 (1)
[3] The roles of miRNAs as potential biomarkers in lung diseases
Alipoor, Shamila D.
Adcock, Ian M.
Garssen, Johan
Mortaz, Esmaeil
Varahram, Mohammad
Mirsaeidi, Mehdi
Velayati, Aliakbar
EUROPEAN JOURNAL OF PHARMACOLOGY, 2016, 791 : 395 - 404
[4] Interrelation between extracellular vesicles miRNAs with chronic lung diseases
Dhar, Rajib
Mukherjee, Sayantanee
Mukerjee, Nobendu
Mukherjee, Dattatreya
Devi, Arikketh
Ashraf, Ghulam Md
Alserihi, Raed F.
Tayeb, Hossam H.
Hashem, Anwar M.
Alexiou, Athanasios
Thorate, Nanasaheb
JOURNAL OF CELLULAR PHYSIOLOGY, 2022, 237 (11) : 4021 - 4036
[5] Lung development and adult lung diseases
Shi, Wei
Bellusci, Saverio
Warburton, David
CHEST, 2007, 132 (02) : 651 - 656
[6] The Role of Exosomal MiRNAs in The Occurrence and Development of Lung Cancer
Yang Yi-Feng
Sun Xin-Ying
Shen Xin-Tong
Ye Ge-Xin
Lou Cheng-Tao
Li Nan
Gong Zhao-Hui
Meng Xiao-Dan
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2020, 47 (03) : 188 - 198
[7] Exosomal miRNAs in Lung Diseases: From Biologic Function to Therapeutic Targets
Guiot, Julien
Struman, Ingrid
Louis, Edouard
Louis, Renaud
Malaise, Michel
Njock, Makon-Sebastien
JOURNAL OF CLINICAL MEDICINE, 2019, 8 (09)
[8] The Role of miRNAs in Extracellular Matrix Repair and Chronic Fibrotic Lung Diseases
Usman, Kauna
Hsieh, Aileen
Hackett, Tillie-Louise
CELLS, 2021, 10 (07)
[9] Recent advances in the development and clinical application of miRNAs in infectious diseases
Nunes, Sara
Bastos, Rana
Marinho, Ananda Isis
Vieira, Raissa
Benicio, Ingra
de Noronha, Maria Alicia
Lirio, Sofia
Brodskyn, Claudia
Tavares, Natalia Machado
NON-CODING RNA RESEARCH, 2025, 10 : 41 - 54
[10] The tumor cytosol miRNAs, fluid miRNAs, and exosome miRNAs in lung cancer
Qin, Xin
Xu, Haisheng
Gong, Wenrong
Deng, Wenbin
FRONTIERS IN ONCOLOGY, 2015, 4

← 1 2 3 4 5 →