Genetic Features of the Widespread Plasmid Coding for the Carbapenemase OXA-48

被引：3
|
作者：
Poirel, Laurent [1 ]
Bonnin, Remy A. [1 ]
Nordmann, Patrice [1 ]
机构：
[1] Univ Paris Sud, Serv Bacteriol Virol, INSERM, Hop Paris,U914, Kbictre, France
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2012年 / 56卷 / 01期
关键词：
OXACILLINASE-MEDIATED RESISTANCE; D BETA-LACTAMASE; KLEBSIELLA-PNEUMONIAE; SPREAD; SEQUENCE; OXA-181; DNA;
D O I：
10.1128/AAC.05289-11
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Complete sequencing of plasmid pOXA-48a carrying the bla(OXA-48) gene from a Klebsiella pneumoniae isolate was performed. Its backbone corresponded to that of an IncL/M-type plasmid, in which the blaOXA-48 gene had been integrated through the acquisition of the Tn1999 composite transposon without any other antibiotic resistance gene. Molecular epidemiology using a collection of international OXA-48 producers revealed the wide diffusion of pOXA-48a or closely related plasmids.
引用
收藏
页码：559 / 562
页数：4
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