Relationship Between Body Weight, PK/PD, and Attack Responses Following Subcutaneous Administration of Lanadelumab in Patients with Hereditary Angioedema

被引：0

作者：

Inhaber, Neil ^{[1
]}

Zuraw, Bruce L. ^{[2
]}

Marier, Jean-Francois ^{[3
]}

Lu, Peng ^{[1
]}

Wang, Yi ^{[1
]}

机构：

[1] Shire, Lexington, MA USA

[2] Univ Calif San Diego, Dept Med, San Diego, CA 92103 USA

[3] Certara Strateg Consulting, Montreal, PQ, Canada

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2019年 / 143卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

115

引用

页码：AB39 / AB39

页数：1

共 7 条

[1] Lanadelumab Provides Sustained PK/PD Following Long-Term Treatment in Patients with Hereditary Angioedema (HAE)
Wang, Yi
Marier, Jean Francois
Chang, Colin
Martin, Patrick
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 145 (02) : AB103 - AB103
[2] SUBCUTANEOUS SELF-ADMINISTRATION OF LANADELUMAB FOR PROPHYLACTIC TREATMENT IN PATIENTS WITH HEREDITARY ANGIOEDEMA (HAE)
Lumry, W.
Busse, P.
Lu, P.
Jain, G.
Nurse, C.
Maurer, M.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2018, 121 (05) : S57 - S57
[3] Pharmacokinetics (PK), Pharmacodynamics (PD), and Exposure-Response (E-R) Analyses Confirm the Effectiveness of Lanadelumab in Patients 2 to <12 Years Old With Hereditary Angioedema (HAE)
Ahmed, Mariam
Wang, Yi
Yu, Ming
Marier, Jean-Francois
Bhattacharya, Indranil
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2023, 151 (02) : AB130 - AB130
[4] RELATIONSHIP BETWEEN BIOLOGICAL-ACTIVITY AND CONCENTRATION OF A LOW-MOLECULAR-WEIGHT HEPARIN (PK-10169) AND UNFRACTIONATED HEPARIN AFTER INTRAVENOUS AND SUBCUTANEOUS ADMINISTRATION
DAWES, J
BARA, L
BILLAUD, E
SAMAMA, M
HAEMOSTASIS, 1986, 16 (02) : 116 - 122
[5] PHARMACOKTNETIC-PHARMACODYNAMIC (PK-PD) MODELLING OF TNF-α SERUM LEVELS IN PATIENTS WITH SEVERE SEPSIS SHOWS NO RELATIONSHIP WITH BODY WEIGHT
Yates, I.
Das, S.
Simonson, S.
INTENSIVE CARE MEDICINE, 2011, 37 : S220 - S220
[6] Population Pharmacokinetic (PK)/Pharmacodynamic (PD) Model of Serum Transthyretin (TTR) following Patisiran-LNP Administration in Healthy Volunteers and Patients with Hereditary TTR-Mediated (hATTR) Amyloidosis With Polyneuropathy
Goel, V.
Gosselin, N.
Jomphe, C.
Attarwala, H.
Zhang, X.
Marier, J.
Robbie, G.
EUROPEAN JOURNAL OF NEUROLOGY, 2018, 25 : 354 - 354
[7] The Relationship Between Abatacept Exposure and CD86 Receptor Occupancy in Rheumatoid Arthritis Patients Following Subcutaneous Administration and Its Association to Patient Outcomes
Abelian, Grigor
Gao, Sheng
Gandhi, Yash
Vakkalagadda, Blisse
Perera, Vidya
Murthy, Bindu
ARTHRITIS & RHEUMATOLOGY, 2019, 71

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