Chemical constituents from the roots of Feroniella lucida

被引：9
|
作者：
Sripisut, Tawanun [1 ]
Cheenpracha, Sarot [2 ]
Laphookhieo, Surat [1 ]
机构：
[1] Mae Fah Luang Univ, Sch Sci, Nat Prod Res Lab, Muang 57100, Chiang Rai, Thailand
[2] Univ Phayao, Sch Sci, Muang 56000, Phayao, Thailand
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2011年 / 13卷 / 06期
关键词：
Feroniella lucida; Rutaceae; cytotoxic activity; antimalarial activity; antituberculosis; CLAUSENA-LANSIUM; A-C; FURANOCOUMARINS; ALKALOIDS; COUMARINS; FUROCOUMARINS; XANTHYLETIN; INHIBITOR; MOIETIES;
D O I：
10.1080/10286020.2011.572878
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new furanocoumarin named lucidafuranocoumarin A (7) together with 13 known coumarins (1-6, 8-14) and four known alkaloids (15-18) was isolated from the roots of Feroniella lucida. Their structures were elucidated on the basis of spectroscopic analysis. Some of the isolates were evaluated for their biological activities, and compound 18 showed strong cytotoxicity against KB (IC50=0.637g/ml) and NCI-H187 (IC50=0.094g/ml) human cancer cell lines, antimalarial activity against Plasmodium falciparum (IC50=0.336g/ml), and antituberculosis activity against Mycobacterium tuberculosis (MIC=6.25g/ml).
引用
收藏
页码：556 / 560
页数：5
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