Channelrhodopsin engineering and exploration of new optogenetic tools

被引：16
|
作者：
Hegemann, Peter [1 ]
Moeglich, Andreas [1 ]
机构：
[1] Humboldt Univ, Dept Biol, D-1040 Berlin, Germany
来源：
NATURE METHODS | 2011年 / 8卷 / 01期
关键词：
D O I：
10.1038/NMETH.F.327
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Rhodopsins from microalgae and eubacteria are powerful tools for manipulating the function of neurons and other cells, but these tools still have limitations. We discuss engineering approaches that can help advance optogenetics.
引用
收藏
页码：39 / 42
页数：4
相关论文
共 50 条
  • [1] Channelrhodopsin engineering and exploration of new optogenetic tools
    Peter Hegemann
    Andreas Möglich
    [J]. Nature Methods, 2011, 8 (1) : 39 - 42
  • [2] Channelrhodopsin variants and new microbial photoreceptors for optogenetic application
    Hegemann, Peter
    Prigge, Matthias
    Schneider, Franziska
    Stierl, Manuela
    [J]. NEUROSCIENCE RESEARCH, 2011, 71 : E24 - E24
  • [3] Induction of Signal Transduction by Using Non-Channelrhodopsin-Type Optogenetic Tools
    Ueda, Yoshibumi
    Sato, Moritoshi
    [J]. CHEMBIOCHEM, 2018, 19 (12) : 1217 - 1231
  • [4] Optogenetic control of medaka behavior with channelrhodopsin
    Seki, Takahide
    Takeuchi, Hideaki
    Ansai, Satoshi
    [J]. DEVELOPMENT GROWTH & DIFFERENTIATION, 2023, 65 (06) : 288 - 299
  • [5] Strategies for Expanding the Operational Range of Channelrhodopsin in Optogenetic Vision
    Mutter, Marion
    Muench, Thomas A.
    [J]. PLOS ONE, 2013, 8 (11):
  • [6] Optogenetic tools for new approaches in oncology research
    Schelch, Karin
    Ingles-Prieto, Alvaro
    Reichhart, Eva
    Ging, Stephanie
    Janovjak, Harald
    Grusch, Michael
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2015, 36 : S7 - S7
  • [7] Channelrhodopsin Photochromic Reactions Provide Multicolor Optogenetic Control
    Spudich, John L.
    [J]. BIOPHYSICAL JOURNAL, 2014, 107 (07) : 1489 - 1490
  • [8] Engineering genetically-encoded tools for optogenetic control of protein activity
    Liu, Qi
    Tucker, Chandra L.
    [J]. CURRENT OPINION IN CHEMICAL BIOLOGY, 2017, 40 : 17 - 23
  • [9] New tools for EEZ exploration
    Denis, J.-F.
    [J]. 2001, Compass Publications Inc. (42)
  • [10] New tools for EEZ exploration
    Denis, JF
    [J]. SEA TECHNOLOGY, 2001, 42 (02) : 73 - 75
12345