KCNQ1 Channel Dysfunction in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying a CALM2-N98S Mutation Associated With Long QT Syndrome

被引：0
|
作者：
Yamamoto, Yuta
Makiyama, Takeru M.
Wuriyanghai, Yimin
Kohjitani, Hirohiko
Hirose, Sayako
Gao, Jingshan
Kashiwa, Asami
Hai, Huang
Aizawa, Takanori
Imamura, Tomohiko
Ishikawa, Taisuke
Ohno, Seiko
Chonabayashi, Kazuhisa
Motomura, Hideki
Yoshida, Yoshinori
Horie, Minoru
Makita, Naomasa
Kimura, Takeshi
机构：
来源：
CIRCULATION | 2019年 / 140卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A13222
引用
收藏
页数：3
相关论文
共 50 条
  • [1] Complex aberrant splicing in the induced pluripotent stem cell-derived cardiomyocytes from a patient with long QT syndrome carrying KCNQ1-A344Aspl mutation
    Wuriyanghai, Yimin
    Makiyama, Takeru
    Sasaki, Kenichi
    Kamakura, Tsukasa
    Yamamoto, Yuta
    Hayano, Mamoru
    Harita, Takeshi
    Nishiuchi, Suguru
    Chen, Jiarong
    Kohjitani, Hirohiko
    Hirose, Sayako
    Yokoi, Fumika
    Gao, Jingshan
    Chonabayashi, Kazuhisa
    Watanabe, Ken
    Ohno, Seiko
    Yoshida, Yoshinori
    Kimura, Takeshi
    Horie, Minoru
    HEART RHYTHM, 2018, 15 (10) : 1566 - 1574
  • [2] Establishment of two human induced pluripotent stem cell lines from familial long QT syndrome type 1 patients carrying KCNQ1 mutation
    Mun, Dasom
    Yoo, Gyeongseo
    Park, Malgeum
    Kang, Ji-Young
    Yun, Nuri
    Joung, Boyoung
    STEM CELL RESEARCH, 2024, 81
  • [3] KCNQ1/KCNE1 K+ Channels Associated with Long QT Syndrome are Expressed in Early Stage Human Embryonic Stem Cell-Derived Cardiomyocytes
    Terrenoire, Cecile
    Wang, George K.
    Adler, Eric
    Kaplan, Aaron D.
    Sampson, Kevin J.
    Lu, Jonathan
    Kass, Robert S.
    BIOPHYSICAL JOURNAL, 2010, 98 (03) : 334A - 334A
  • [4] Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
    Matsa, Elena
    Rajamohan, Divya
    Dick, Emily
    Young, Lorraine
    Mellor, Ian
    Staniforth, Andrew
    Denning, Chris
    EUROPEAN HEART JOURNAL, 2011, 32 (08) : 952 - 962
  • [5] DRUG EVALUATION IN CARDIOMYOCYTES DERIVED FROM HUMAN INDUCED PLURIPOTENT STEM CELLS CARRYING A LONG QT SYNDROME TYPE 2 MUTATION
    Matsa, E.
    Rajamohan, D.
    Dick, E.
    Young, L.
    Mellor, I.
    Staniforth, A.
    Denning, C.
    HEART, 2011, 97 (20) : 8 - 8
  • [6] Characterization of a novel KCNQ1 mutation for type 1 long QT syndrome and assessment of the therapeutic potential of a novel IKs activator using patient-specific induced pluripotent stem cell-derived cardiomyocytes
    Dongrui Ma
    Heming Wei
    Jun Lu
    Dou Huang
    Zhenfeng Liu
    Li Jun Loh
    Omedul Islam
    Reginald Liew
    Winston Shim
    Stuart A Cook
    Stem Cell Research & Therapy, 6
  • [7] Characterization of a novel KCNQ1 mutation for type 1 long QT syndrome and assessment of the therapeutic potential of a novel IKs activator using patient-specific induced pluripotent stem cell-derived cardiomyocytes
    Ma, Dongrui
    Wei, Heming
    Lu, Jun
    Huang, Dou
    Liu, Zhenfeng
    Loh, Li Jun
    Islam, Omedul
    Liew, Reginald
    Shim, Winston
    Cook, Stuart A.
    STEM CELL RESEARCH & THERAPY, 2015, 6
  • [8] Generation of a human embryonic stem cell line WAe009-A-79 carrying a long QT syndrome mutation in KCNQ1
    Wang, Hongyue
    Guo, Tianwei
    Lan, Feng
    STEM CELL RESEARCH, 2023, 70
  • [9] Modeling Short QT Syndrome Using Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
    El-Battrawy, Ibrahim
    Lan, Huan
    Cyganek, Lukas
    Zhao, Zhihan
    Li, Xin
    Buljubasic, Fanis
    Lang, Siegfried
    Yucel, Gokhan
    Sattler, Katherine
    Zimmermann, Wolfram-Hubertus
    Utikal, Jochen
    Wieland, Thomas
    Ravens, Ursula
    Borggrefe, Martin
    Zhou, Xiao-Bo
    Akin, Ibrahim
    JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2018, 7 (07):
  • [10] Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes
    Rocchetti, Marcella
    Sala, Luca
    Dreizehnter, Lisa
    Crotti, Lia
    Sinnecker, Daniel
    Mura, Manuela
    Pane, Luna Simona
    Altomare, Claudia
    Torre, Eleonora
    Mostacciuolo, Gaspare
    Severi, Stefano
    Porta, Alberto
    De Ferrari, Gaetano M.
    George, Alfred L., Jr.
    Schwartz, Peter J.
    Gnecchi, Massimiliano
    Moretti, Alessandra
    Zaza, Antonio
    CARDIOVASCULAR RESEARCH, 2017, 113 (05) : 531 - 541
12345