Changes in land-use and land-cover (LULC) in urban areas affect the natural environment, especially urban green spaces (UGS). The present study examines the loss of UGS due to LULC transformation at different periods to predict the future vulnerable zone of UGS, based on the 'Pressure-State-Response' framework. To calculate the weight of each factor, a combined Analytical Hierarchical Process and Fuzzy Comprehensive Evaluation method have been used. An integrated multilayer perceptron based artificial neural network and Markov chain (MLP-ANN-MC) model has been employed to predict the UGS vulnerable area in Kolkata. Results indicated that growth rates of built-up area, land-use dynamic degree, change intensity index, and proximity factors are the major responsible for UGS vulnerability. Applying the MLP-ANN-MC model, future vulnerable zones were identified for management and conservation of UGS. The methodology developed and demonstrated in this study expands LULC change analysis and provide a new dimension for UGS vulnerability assessment.