Retymicin, galtamycin B, saquayamycin Z and ribofuranosyllumichrome, novel secondary metabolites from Micromonospora sp Tu 6368 -: II.: Structure elucidation

被引：32
|
作者：
Ströch, K
Zeeck, A
Antal, N
Fiedler, HP
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
[2] Univ Tubingen, Inst Mikrobiol, D-72076 Tubingen, Germany
来源：
JOURNAL OF ANTIBIOTICS | 2005年 / 58卷 / 02期
关键词：
structure elucidation; Micromonospora; angucyclinones; tetracenequione glycosides; saquayamycin Z; lumichromes;
D O I：
10.1038/ja.2005.13
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A detailed screening of the secondary metabolite pattern from Micromonospora sp. strain Tu 6368 resulted in the isolation of ten compounds belonging to five different structural families. The structures of the novel compounds 1-(alpha-ribofuranosyl)-lumichrome (3), retymicin (7), galtamycin B (11) and saquayamycin Z (14) were assigned by spectroscopic methods and chemical transformations. This strain fits our hypothesis that the metabolite analysis of biosynthetically talented strains leads readily to novel compounds.
引用
收藏
页码：103 / 110
页数：8
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