Combination vaccine strategies to prevent enteric infections

被引:14
|
作者
Walker, Richard [1 ]
Dull, Peter [2 ]
机构
[1] Bill & Melinda Gates Fdn, Seattle, WA USA
[2] PATH, 455 Massachusetts Ave NW, Washington, DC 20001 USA
基金
比尔及梅琳达.盖茨基金会;
关键词
Combined vaccines; Shigella; ETEC; Enterotoxigenic Escherichia coli; Regulatory strategy; DIARRHEAL DISEASE; CHILDREN;
D O I
10.1016/j.vaccine.2017.06.076
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
New vaccine candidates entering the current routine immunization schedule can best be accommodated as combination vaccines. A combined Shigella and enterotoxigenic E. coli (ETEC) vaccine could greatly benefit children in disease-endemic areas. New candidates are getting closer to being able to meet these needs, but they raise numerous strategic questions related to presentation, formulation, and regulatory approach. The "Combination Vaccine Strategies to Prevent Enteric Infections" workshop at the 2016 Vaccines Against Shigella and ETEC (VASE) Conference examined some of the considerations for developing such vaccines against enteric pathogens. (C) 2017 Published by Elsevier Ltd.
引用
收藏
页码:6790 / 6792
页数:3
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