Federated discovery and sharing of genomic data using Beacons

被引：52

作者：

Fiume, Marc ^{[1
]}

Cupak, Miroslav ^{[1
]}

Keenan, Stephen ^{[2
,3
]}

Rambla, Jordi ^{[4
]}

de la Torre, Sabela ^{[4
]}

Dyke, Stephanie O. M. ^{[5
]}

Brookes, Anthony J. ^{[6
]}

Carey, Knox ^{[7
]}

Lloyd, David ^{[8
]}

Goodhand, Peter ^{[2
,9
]}

Haeussler, Maximilian ^{[10
]}

Baudis, Michael ^{[11
,12
]}

Stockinger, Heinz ^{[12
]}

Dolman, Lena ^{[2
,13
]}

Lappalainen, Ilkka ^{[3
,14
]}

Tornroos, Juha ^{[14
]}

Linden, Mikael ^{[14
]}

Spalding, J. Dylan ^{[3
]}

Ur-Rehman, Saif ^{[3
]}

Page, Angela ^{[2
,15
]}

Flicek, Paul ^{[3
,13
]}

Sherry, Stephen ^{[16
]}

Haussler, David ^{[10
]}

Varma, Susheel ^{[8
]}

Saunders, Gary ^{[8
]}

Scollen, Serena ^{[8
]}

机构：

[1] DNAstack, Toronto, ON, Canada

[2] Global Alliance Genom & Hlth, Toronto, ON, Canada

[3] European Bioinformat Inst, European Mol Biol Lab, Wellcome Genome Campus, Cambridge, England

[4] Ctr Regulacio Genom, Barcelona, Spain

[5] McGill Univ, Dept Human Genet, Ctr Genom & Policy, Montreal, PQ, Canada

[6] Univ Leicester, Dept Genet, Leicester, Leics, England

[7] Genecloud, Sunnyvale, CA USA

[8] ELIXIR Hub, Wellcome Genome Campus, Cambridge, England

[9] Ontario Inst Canc Res, Toronto, ON, Canada

[10] Univ Calif Santa Cruz, Genom Inst, Santa Cruz, CA 95064 USA

[11] Univ Zurich, Dept Mol Life Sci, Zurich, Switzerland

[12] SIB, Lausanne, Switzerland

[13] Wellcome Trust Sanger Inst, Wellcome Genome Campus, Cambridge, England

[14] CSC IT Ctr Sci Ltd, Espoo, Finland

[15] Broad Inst MIT & Harvard, Cambridge, MA 02142 USA

[16] US Natl Lib Med, Natl Ctr Biotechnol Informat, Bethesda, MD USA

来源：

NATURE BIOTECHNOLOGY | 2019年 / 37卷 / 03期

基金：

欧盟地平线“2020”; 英国惠康基金; 加拿大健康研究院;

关键词：

MATCHMAKER EXCHANGE; SEQUENCE VARIATION; NETWORK;

D O I：

10.1038/s41587-019-0046-x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：220 / 224

页数：6

共 50 条

[1] Federated discovery and sharing of genomic data using Beacons
Marc Fiume
Miroslav Cupak
Stephen Keenan
Jordi Rambla
Sabela de la Torre
Stephanie O. M. Dyke
Anthony J. Brookes
Knox Carey
David Lloyd
Peter Goodhand
Maximilian Haeussler
Michael Baudis
Heinz Stockinger
Lena Dolman
Ilkka Lappalainen
Juha Törnroos
Mikael Linden
J. Dylan Spalding
Saif Ur-Rehman
Angela Page
Paul Flicek
Stephen Sherry
David Haussler
Susheel Varma
Gary Saunders
Serena Scollen
[J]. Nature Biotechnology, 2019, 37 : 220 - 224
[2] Publisher Correction: Federated discovery and sharing of genomic data using Beacons
Marc Fiume
Miroslav Cupak
Stephen Keenan
Jordi Rambla
Sabela de la Torre
Stephanie O. M. Dyke
Anthony J. Brookes
Knox Carey
David Lloyd
Peter Goodhand
Maximilian Haeussler
Michael Baudis
Heinz Stockinger
Lena Dolman
Ilkka Lappalainen
Juha Törnroos
Mikael Linden
J. Dylan Spalding
Saif Ur-Rehman
Angela Page
Paul Flicek
Stephen Sherry
David Haussler
Susheel Varma
Gary Saunders
Serena Scollen
[J]. Nature Biotechnology, 2019, 37 : 480 - 480
[3] Federated discovery and sharing of genomic data using Beacons (vol 37, pg 220, 2019)
Fiume, Marc
Cupak, Miroslav
Keenan, Stephen
Rambla, Jordi
de la Torre, Sabela
Dyke, Stephanie O. M.
Brookes, Anthony J.
Carey, Knox
Lloyd, David
Goodhand, Peter
Haeussler, Maximilian
Baudis, Michael
Stockinger, Heinz
Dolman, Lena
Lappalainen, Ilkka
Tornroos, Juha
Linden, Mikael
Spalding, J. Dylan
Ur-Rehman, Saif
Page, Angela
Flicek, Paul
Sherry, Stephen
Haussler, David
Varma, Susheel
Saunders, Gary
Scollen, Serena
[J]. NATURE BIOTECHNOLOGY, 2019, 37 (04) : 480 - 480
[4] A federated ecosystem for sharing genomic, clinical data
The Global Alliance for Genomics and Health
[J]. SCIENCE, 2016, 352 (6291) : 1278 - 1280
[5] Privacy Risks from Genomic Data-Sharing Beacons
Shringarpure, Suyash S.
Bustamante, Carlos D.
[J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2015, 97 (05) : 631 - 646
[6] Federated sharing and processing of genomic datasets for tertiary data analysis
Canakoglu, Arif
Pinoli, Pietro
Gulino, Andrea
Nanni, Luca
Masseroli, Marco
Ceri, Stefano
[J]. BRIEFINGS IN BIOINFORMATICS, 2021, 22 (03)
[7] Generalized genomic data sharing for differentially private federated learning
Al Aziz, Md Momin
Anjum, Md Monowar
Mohammed, Noman
Jiang, Xiaoqian
[J]. JOURNAL OF BIOMEDICAL INFORMATICS, 2022, 132
[8] The effect of kinship in re-identification attacks against genomic data sharing beacons
Ayoz, Kerem
Aysen, Miray
Ayday, Erman
Cicek, A. Ercument
[J]. BIOINFORMATICS, 2020, 36 : I903 - I910
[9] Re-identification of individuals in genomic data-sharing beacons via allele inference
von Thenen, Nora
Ayday, Erman
Cicek, A. Ercument
[J]. BIOINFORMATICS, 2019, 35 (03) : 365 - 371
[10] Big pediatric cancer genomic data: Discovery, precision medicine, and data sharing
Zhang, Jinghui
[J]. CLINICAL CANCER RESEARCH, 2021, 27 (05)

← 1 2 3 4 5 →