Ultrastructural analysis of interactions of staphylococci with mono- and polynuclear phagocytes in nonphlogogenic and phlogogenic reaction

被引：0

作者：

Saprykin, VP ^{[1
]}

Galankin, VN ^{[1
]}

机构：

[1] Russian Univ Peoples Friendship, Dept Pathol Physiol, Dept Pathol Anat, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1998年 / 125卷 / 03期

关键词：

neutrophil; Staphylococcus; macrophage; phagolysosome;

D O I：

10.1007/BF02496889

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Antibacterial activity of neutrophils and peritoneal macrophages toward massive doses of Staphylococcus aureus is studied in vivo. Two types of antibacterial response are revealed: non-phlogogenic (physiological) and phlogogenic (inflammatory). Nonphlogogenic reaction is characterized by pronounced antibacterial effect of phagocytes on cocci. Transition to phlogogenic response is accompanied by impaired function of phagocytes involving their self-destruction and disintegration, which decreases their antibacterial activity and promotes inflammation.

引用

页码：304 / 308

页数：5

共 9 条

[1] Ultrastructural analysis of interactions of staphylococci with mono- and polynuclear phagocytes in nonphlogogenic and phlogogenic reaction
V. P. Saprykin
V. N. Galankin
Bulletin of Experimental Biology and Medicine, 1998, 125 : 304 - 308
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