Advagraf®, a once-daily prolonged release tacrolimus formulation, in kidney transplantation: literature review and guidelines from a panel of experts

被引:26
|
作者
Caillard, Sophie [1 ]
Moulin, Bruno [1 ]
Buron, Fanny [2 ]
Mariat, Christophe [3 ]
Audard, Vincent [4 ]
Grimbert, Philippe [4 ]
Marquet, Pierre [5 ]
机构
[1] Strasbourg Univ Hosp, Nephrol & Transplant Dept, Strasbourg, France
[2] Hop Edouard Herriot, Hosp Civils Lyon, Transplant Nephrol & Immunol Dept, Lyon, France
[3] St Etienne Univ Hosp, North Hosp, Nephrol Dialysis & Renal Transplants Dept, St Priest En Jarez, France
[4] Henri Mondor Hosp, AP HP, Nephrol & Transplant Dept, IFRNT, Creteil, France
[5] Univ Limoges, CHU Limoges, INSERM, UMR 850, Limoges, France
关键词
clinical practice; extended release tacrolimus; immunosuppression; kidney transplant; therapeutic drug monitoring; TWICE-DAILY TACROLIMUS; SOLID-ORGAN TRANSPLANTATION; SINGLE-CENTER EXPERIENCE; RANDOMIZED PHASE-III; RENAL-TRANSPLANTATION; CLINICAL PHARMACOKINETICS; GRAFT FUNCTION; DAILY PROGRAF; RECIPIENTS; CONVERSION;
D O I
10.1111/tri.12674
中图分类号
R61 [外科手术学];
学科分类号
摘要
The efficacy and safety of tacrolimus twice-a-day (BID) and once-a-day (QD) formulations are similar. However, the available information regarding the initiation and management of tacrolimus QD is sparse and practical information is lacking. A panel of French experts extensively reviewed the available literature on tacrolimus pharmacokinetics, clinical efficacy, and safety in kidney transplantation and, based on their own day-to-day experience, provided the practitioners with practical guidelines for the daily use and management of tacrolimus QD in de novo initiation or early conversion.
引用
收藏
页码:860 / 869
页数:10
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