Synthesis and Antibacterial Activity Studies of 8,9-Dihydro [7h] Benzo 1,2,4-Oxadiazoles and its Coumarin Derivatives

被引:12
|
作者
Srinivas, B. [1 ,2 ]
Suryachandram, Jettiboina [1 ]
Devi, Y. Katyayani [1 ]
Rao, Koya Prabhakara [1 ]
机构
[1] Vignans Fdn Sci Technol & Res VFSTR Univ, Dept Sci & Humanities, NGML, Guntur 522213, Andhra Pradesh, India
[2] Guru Nanak Inst Tech Campus, Dept Humanities & Sci, Hyderabad, Telangana, India
关键词
DESIGN; FORM;
D O I
10.1002/jhet.2960
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Synthesis, characterization, and antibacterial active studies of 12 coumarin derivatives were described in this study. Synthesis was achieved by the reaction of 4-carbonyl chloride with 1,2-dichloroethane as a solvent, in moderate to good yields. The structures of all the newly synthesized molecules were assigned by spectral data and elemental analysis. The synthesized compounds were screened for their antibacterial activities strains using paper disc method.
引用
收藏
页码:3730 / 3734
页数:5
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