Treatment of Idiopathic Membranous Nephropathy

被引:60
|
作者
Waldman, Meryl [1 ]
Austin, Howard A., III [1 ]
机构
[1] NIDDKD, Kidney Dis Sect, NIH, Bethesda, MD 20892 USA
来源
基金
美国国家卫生研究院;
关键词
RANDOMIZED CONTROLLED-TRIAL; COMPARING METHYLPREDNISOLONE PLUS; PROLIFERATIVE LUPUS NEPHRITIS; CONVERTING ENZYME-INHIBITION; LONG-TERM TREATMENT; MYCOPHENOLATE-MOFETIL; NEPHROTIC SYNDROME; WEGENERS-GRANULOMATOSIS; UNTREATED PATIENTS; HEYMANN NEPHRITIS;
D O I
10.1681/ASN.2012010058
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Exciting progress recently has been made in our understanding of idiopathic membranous nephropathy, as well as treatment of this disease. Here, we review important advances regarding the pathogenesis of membranous nephropathy. We will also review the current approach to treatment and its limitations and will highlight new therapies that are currently being explored for this disease including Rituximab, mycophenolate mofetil, and adrenocorticotropic hormone, with an emphasis on results of the most recent clinical trials.
引用
收藏
页码:1617 / 1630
页数:14
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