A Predictive and Preventive Model for Onset of Alzheimer's Disease

被引:2
|
作者
Singhania, Udit [1 ]
Tripathy, Balakrushna [2 ]
Hasan, Mohammad Kamrul [3 ]
Anumbe, Noble C. [4 ]
Alboaneen, Dabiah [5 ]
Ahmed, Fatima Rayan Awad [6 ]
Ahmed, Thowiba E. [5 ]
Nour, Manasik M. Mohamed [7 ]
机构
[1] Vellore Inst Technol, Sch Comp Sci & Engn, Vellore, Tamil Nadu, India
[2] Vellore Inst Technol, Sch Informat Technol & Engn, Vellore, Tamil Nadu, India
[3] Univ Kebangsaan Malaysia, Fac Informat Sci & Technol, Ctr Cyber Secur, Bangi, Malaysia
[4] Univ South Carolina, Dept Mech Engn, Columbia, SC 29208 USA
[5] Imam Abdulrahman Bin Faisal Univ, Coll Sci & Humanities, Dept Comp Sci, Jubail Ind City, Saudi Arabia
[6] Prince Sattam Bin Abdulaziz Univ, Dept Comp Sci, Coll Comp Engn & Sci, Al Kharj, Saudi Arabia
[7] Prince Sattam Bin Abdulaziz Univ, Dept Math, Coll Sci & Humanity, Al Kharj, Saudi Arabia
关键词
machine learning; Alzheimer's disease; prediction; prevention; convolutional neural networks; support vector machine; OPEN ACCESS SERIES; MRI DATA; DEMENTIA; ALGORITHM;
D O I
10.3389/fpubh.2021.751536
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Alzheimer's Disease (AD) is a neurodegenerative irreversible brain disorder that gradually wipes out the memory, thinking skills and eventually the ability to carry out day-to-day tasks. The amount of AD patients is rapidly increasing due to several lifestyle changes that affect biological functions. Detection of AD at its early stages helps in the treatment of patients. In this paper, a predictive and preventive model that uses biomarkers such as the amyloid-beta protein is proposed to detect, predict, and prevent AD onset. A Convolution Neural Network (CNN) based model is developed to predict AD at its early stages. The results obtained proved that the proposed model outperforms the traditional Machine Learning (ML) algorithms such as Logistic Regression, Support Vector Machine, Decision Tree Classifier, and K Nearest Neighbor algorithms.
引用
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页数:12
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