Investigation of beam delivery time for synchrotron-based proton pencil beam scanning system with novel scanning mode

被引:13
|
作者
Liang, Xiaoying [1 ]
Liu, Chunbo [2 ]
Furutani, Keith M. [1 ]
Shen, Jiajian [3 ]
Bues, Martin [3 ]
Dougherty, Jingjing M. [1 ]
Li, Heng [4 ]
Parisi, Alessio [1 ]
Shrestha, Deepak K. [1 ]
Yaddanpudi, Sridhar [1 ]
Beltran, Chris [1 ]
机构
[1] Mayo Clin Florida, Dept Radiat Oncol, Jacksonville, FL 32224 USA
[2] Zhengzhou Univ, Affiliated Hosp 1, Dept Radiat Oncol, Zhengzhou 450052, Peoples R China
[3] Mayo Clin Arizona, Dept Radiat Oncol, Phoenix, AZ 85054 USA
[4] Johns Hopkins Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD 21287 USA
来源
PHYSICS IN MEDICINE AND BIOLOGY | 2022年 / 67卷 / 17期
关键词
INTRAFRACTION MOTION; THERAPY;
D O I
10.1088/1361-6560/ac8410
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Objective. To investigate synchrotron-based proton pencil beam scanning (PBS) beam delivery time (BDT) using novel continuous scanning mode. Approach. A BDT calculation model was developed for the Hitachi particle therapy system. The model was validated against the measured BDT of 36 representative clinical proton PBS plans with discrete spot scanning (DSS) in the current Hitachi proton therapy system. BDTs were calculated with the next generation using Mayo Clinic Florida system operating parameters for conventional DSS, and novel dose driven continuous scanning (DDCS). BDTs of DDCS with and without Break Spots were investigated. Main results. For DDCS without Break Spots, the use of Stop Ratio to control the transit dose largely reduced the beam intensity and consequently, severely prolonged the BDT. DDCS with Break Spots was able to maintain a sufficiently high beam intensity while controlling transit dose. In DDCS with Break Spots, tradeoffs were made between beam intensity and number of Break Spots. Therefore, BDT decreased with increased beam intensity but reached a plateau for beam intensity larger than 10 MU s(-1). Averaging over all clinical plans, BDT was reduced by 10% for DDCS with Break Spots compared to DSS. Significance. DDCS with Break Spots reduced BDT. DDCS has the potential to further reduce BDT under the ideal scenario which requests both stable beam intensity extraction and accurately modelling the transit dose. Further investigation is warranted.
引用
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页数:14
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