Blood neurofilament light chain levels are elevated in paediatric patients with multiple sclerosis and reduced under disease-modifying treatment

被引：0
|
作者：
Reinert, M. -C. [1 ]
Kropshofer, H. [2 ]
Barro, C. [3 ,4 ]
Wuerfel, J. [5 ,6 ]
Benkert, P. [3 ,4 ]
Michalak, Z. [3 ,4 ]
Brueck, W. [7 ]
Huppke, P. [1 ]
Tomic, D. [2 ]
Leppert, D. [2 ]
Kuhle, J. [3 ,4 ]
Gaertner, J. [1 ]
机构：
[1] Georg August Univ Gottingen, Univ Med Ctr Gottingen, Div Pediat Neurol, Dept Pediat & Adolescent Med, Gottingen, Germany
[2] Novartis Pharma AG, Basel, Switzerland
[3] Univ Basel, Univ Hosp Basel, Dept Med, Neurol Clin & Policlin, Basel, Switzerland
[4] Univ Basel, Univ Hosp Basel, Dept Biomed & Clin Res, Neurol Clin & Policlin, Basel, Switzerland
[5] Med Image Anal Ctr MIAC AG, Basel, Switzerland
[6] Univ Basel, Dept Biomed Engn, Basel, Switzerland
[7] Georg August Univ Gottingen, Univ Med Ctr Gottingen, Inst Neuropathol, Gottingen, Germany
来源：
MULTIPLE SCLEROSIS JOURNAL | 2018年 / 24卷
基金：
新加坡国家研究基金会; 欧盟地平线“2020”;
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
P1793
引用
收藏
页码：1023 / 1023
页数：1
相关论文
共 50 条
  • [1] Elevated neurofilament light chain levels in progressive multiple sclerosis effectively reduced by cladribine treatment
    Yildiz, O.
    Mao, Z.
    Adams, A.
    Dubuisson, N.
    Allen-Philbey, K.
    Giovannoni, G.
    Malaspina, A.
    Baker, D.
    Gnanapavan, S.
    Schmierer, K.
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 : 949 - 949
  • [2] Blood neurofilament light chain levels are elevated in multiple sclerosis and correlate with disease activity.
    Kuhle, J.
    Barro, C.
    Brachat, A. H.
    Valentin, M. -A.
    Hillenbrand, R.
    Kropshofer, H.
    Kappos, L.
    Dahlke, F.
    MULTIPLE SCLEROSIS JOURNAL, 2016, 22 : 828 - 828
  • [3] Neurofilament Light Chain Levels In Pregnant Multiple Sclerosis Patients
    Pablo Cuello, Juan
    Martinez Gines, Maria Luisa
    Kuhle, Jens
    Garcia Dominguez, Jose Manuel
    Lozano Ros, Alberto
    Romero Delgado, Fernando
    Higueras, Yolanda
    Meldana Rivera, Ariana
    Goicochea Briceno, Haydee
    Garcia Tizon, Santiago
    de-Leon Ruiz, Juan
    Alvarez Lafuente, Roberto
    Inmaculada Dominguez-Mozo, Maria
    Perez-Perez, Silvia
    Heras, Silvia Medina
    Velasco, Jose Ignacio Fernandez
    Tejeda-Velarde, Amalia
    De Andres, Clara
    Villar, Luisa Maria
    NEUROLOGY, 2019, 92 (15)
  • [4] Examination of the neurofilament light chain in the blood of patients with multiple sclerosis
    Turcani, P.
    Vitkova, M.
    CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE, 2023, 86 (04) : 286 - 287
  • [5] Blood neurofilament light levels are reduced following ocrelizumab treatment in patients with relapsing and primary progressive multiple sclerosis
    Bar-or, A.
    Thanei, G. -A.
    Harp, C.
    Cross, A.
    Hauser, S.
    Jia, X.
    Kuhle, J.
    Leppert, D.
    Model, F.
    Fiore, D.
    Koendgen, H.
    Hendricks, R.
    Fischer, S.
    Manfrini, M.
    Herman, A.
    EUROPEAN JOURNAL OF NEUROLOGY, 2020, 27 : 197 - 197
  • [6] Interrupting disease modifying treatment for pregnancy in multiple sclerosis - effect on disease activity and serum neurofilament light chain
    Yaldizli, O.
    Benkert, P.
    Bedussi, F.
    Schaedelin, S.
    Oechtering, J.
    Ceschi, A.
    Maceski, A.
    Orleth, A.
    Salmen, A.
    Granziera, C.
    Achtnichts, L.
    Pot, C.
    Du Pasquier, R.
    Lalive, P.
    Mueller, S.
    Kappos, L.
    Gobbi, C.
    Leppert, D.
    Zecca, C.
    Kuhle, J.
    MULTIPLE SCLEROSIS JOURNAL, 2020, 26 (3_SUPPL) : 46 - 46
  • [7] Neurofilament light chain is a useful biomarker in paediatric multiple sclerosis
    Reinert, M. -C.
    Barro, C.
    Michalak, Z.
    Brueck, W.
    Huppke, P.
    Kropshofer, H.
    Tomic, D.
    Leppert, D.
    Kuhle, J.
    Gaertner, J.
    MULTIPLE SCLEROSIS JOURNAL, 2018, 24 : 337 - 338
  • [8] Serum Neurofilament Light Chain Levels as a Biomarker of Disease Activity, Progression and Treatment Response in Patients with Multiple Sclerosis
    Fabis-Pedrini, Marzena
    Kaskow, Belinda
    Trend, Stephanie
    Carroll, William
    Walters, Sue
    Maceski, Aleksandra
    Kuhle, Jens
    Kermode, Allan
    MULTIPLE SCLEROSIS JOURNAL, 2023, 29 (07) : NP2 - NP2
  • [9] Siponimod Reduces Neurofilament Light Chain Blood Levels in Secondary Progressive Multiple Sclerosis Patients
    Kuhle, Jens
    Kropshofer, Harald
    Barro, Christian
    Meinert, Rolf
    Haring, Dieter A.
    Leppert, David
    Tomic, Davorka
    Dahlke, Frank
    Kappos, Ludwig
    NEUROLOGY, 2018, 90
  • [10] Serum Neurofilament Light Chain Levels in Patients With Presymptomatic Multiple Sclerosis
    Bjornevik, Kjetil
    Munger, Kassandra L.
    Cortese, Marianna
    Barro, Christian
    Healy, Brian C.
    Niebuhr, David W.
    Scher, Ann I.
    Kuhle, Jens
    Ascherio, Alberto
    JAMA NEUROLOGY, 2020, 77 (01) : 58 - 64
12345