A Multicenter Phase II Randomized Trial of a HIF-Prolyl Hydroxylase Inhibitor for Neuroprotection in High Risk Thoracic Aortic Repair

被引:0
|
作者
Messe, Steven [5 ]
Demopoulos, Laura [4 ]
Haws, Thomas [4 ]
Khonezhad, Ali [1 ]
Leshnower, Bradley [3 ]
Caselli, Joseph [7 ]
Appoo, Jehangir [8 ]
Hughes, G. [2 ]
Reece, T. [9 ]
Brinster, Derek [6 ]
Kasner, Scott [10 ]
Kern, John [12 ]
Desai, Nimesh [11 ]
Ballard, Victoria [4 ]
Fang, Frank [4 ]
Lepore, John [4 ]
Bavaria, Joseph [11 ]
机构
[1] Cedars Sinai Med Ctr, Dept Surg, Los Angeles, CA USA
[2] Duke Univ, Dept Surg, Durham, NC USA
[3] Emory Univ, Dept Surg, Atlanta, GA USA
[4] GlaxoSmithKline, King Of Prussia, PA USA
[5] Hosp Univ Penn, 3400 Spruce St, Philadelphia, PA 19104 USA
[6] North Shore Long Isl Jewish Hosp, Dept Surg, New York, NY USA
[7] Texas Heart Inst, Dept Surg, Houston, TX 77025 USA
[8] Univ Calgary, Dept Surg, Calgary, AB, Canada
[9] Univ Colorado, Dept Surg, Aurora, CO USA
[10] Univ Penn, Philadelphia, PA 19104 USA
[11] Univ Penn, Dept Surg, Philadelphia, PA 19104 USA
[12] Univ Virginia, Dept Surg, Charlottesville, VA USA
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
S7.008
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Zinc Inhibits HIF-Prolyl Hydroxylase Inhibitor-Aggravated VSMC Calcification Induced by High Phosphate
    Nagy, Annamaria
    Petho, David
    Gall, Tamas
    Zavaczki, Erzsebet
    Nyitrai, Monika
    Posta, Jozsef
    Zarjou, Abolfazl
    Agarwal, Anupam
    Balla, Gyorgy
    Balla, Jozsef
    FRONTIERS IN PHYSIOLOGY, 2020, 10
  • [2] Effect of a HIF-prolyl hydroxylase inhibitor on aortic pressure, heart rate and peak right ventricular pressure in rats exposed to acute hypoxia
    Kohrs, Loren
    Renninger, Jon
    Murphy, Dennis
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2016, 81 : 378 - 378
  • [3] Endovascular treatment of thoracic aortic aneurysms: Results of the phase II multicenter trial of the GORE TAG thoracic endoprosthesis
    Makaroun, MS
    Dillavou, ED
    Kee, ST
    Sicard, G
    Chaikof, E
    Bavaria, J
    Williams, D
    Cambria, RP
    Mitchell, RS
    JOURNAL OF VASCULAR SURGERY, 2005, 41 (01) : 1 - 8
  • [4] Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Multicenter Randomized Phase II Trial
    Uphaus, Timo
    Richards, Toby
    Weimar, Christian
    Neugebauer, Hermann
    Poli, Sven
    Weissenborn, Karin
    Imray, Christopher
    Michalski, Dominik
    Rashid, Hisham
    Loftus, Ian
    Rummey, Christian
    Ritter, Martin
    Hauser, Till-Karsten
    Munch, Gotz
    Groeschel, Klaus
    Poppert, Holger
    STROKE, 2022, 53 (09) : 2718 - 2729
  • [5] Adjuvant Zoledronic Acid in High-Risk Giant Cell Tumor of Bone: A Multicenter Randomized Phase II Trial
    Lipplaa, Astrid
    Kroep, Judith R.
    van der Heijden, Lizz
    Jutte, Paul C.
    Hogendoorn, Pancras C. W.
    Dijkstra, Sander
    Gelderblom, Hans
    ONCOLOGIST, 2019, 24 (07): : 889 - +
  • [6] Endovascular stent grafting versus open surgical repair of descending thoracic aortic aneurysms in low-risk patients: A multicenter comparative trial
    Bavaria, Joseph E.
    Appoo, Jehangir J.
    Makaroun, Michel S.
    Verter, Joel
    Yu, Zi-Fan
    Mitchell, R. Scott
    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2007, 133 (02): : 369 - U17
  • [7] Adjuvant chemoradiation combined with immunotherapy for patients with high-risk resectable extrahepatic cholangiocarcinoma and gallbladder cancer: A phase II, multicenter, randomized controlled trial (ACCORD trial).
    Kuang, Ming
    Peng, Zhenwei
    Shen, Shun-Li
    Chen, Shuling
    Xiao, Han
    JOURNAL OF CLINICAL ONCOLOGY, 2025, 43 (4_SUPPL)
  • [8] 1-Year Outcomes of a Multicenter Randomized Controlled Trial of the Ankura II Thoracic Endoprosthesis for the Endovascular Treatment of Stanford Type B Aortic Dissections
    Shu, Chang
    He, Hao
    Fu, Weiguo
    Guo, Wei
    Li, Ming
    Xi, Erping
    Guo, Shuguang
    Chen, Xueming
    Xiao, Zhanxiang
    Yu, Shiqiang
    Huang, Jianhua
    Dai, Xiangchen
    Wang, Zhiwei
    Li, Wei
    Zheng, Qingshan
    Li, Quanming
    Wang, Lunchang
    Li, Xin
    Wang, Junwei
    Gu, Feng
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [9] A Novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (GSK1278863) for Anemia in CKD: A 28-Day, Phase 2A Randomized Trial
    Brigandi, Richard A.
    Johnson, Brendan
    Oei, Coreen
    Westerman, Mark
    Olbina, Gordana
    de Zoysa, Janak
    Roger, Simon D.
    Sahay, Manisha
    Cross, Nicholas
    McMahon, Lawrence
    Guptha, Veerabhadra
    Smolyarchuk, Elena A.
    Singh, Narinder
    Russ, Steven F.
    Kumar, Sanjay
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2016, 67 (06) : 861 - 871
  • [10] Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial
    Gillespie, Erin F.
    Yang, Joanna C.
    Mathis, Noah J.
    Marine, Catherine B.
    White, Charlie
    Zhang, Zhigang
    Barker, Christopher A.
    Kotecha, Rupesh
    McIntosh, Alyson
    Vaynrub, Max
    Bartelstein, Meredith K.
    Mitchell, Aaron
    Guttmann, David M.
    Yerramilli, Divya
    Higginson, Daniel S.
    Yamada, Yoshida J.
    Kohutek, Zachary A.
    Powell, Simon N.
    Tsai, Jillian
    Yang, Jonathan T.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (01) : 38 - +