Dogger Bank Itch revisited:: isolation of (2-hydroxyethyl) dimethylsulfoxonium chloride as a cytotoxic constituent from the marine sponge Theonella aff. mirabilis

被引：5

作者：

Warabi, K

Nakao, Y

Matsunaga, S

Fukuyama, T

Kan, T

Yokoshima, S

Fusetani, N ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Agr & Life Sci, Lab Aquat Nat Prod Chem, Bunkyo Ku, Tokyo 1138657, Japan

[2] Univ Tokyo, Grad Sch Pharmaceut Sci, Tokyo 1130033, Japan

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 2001年 / 128卷 / 01期

关键词：

cytotoxic; Dogger Bank Itch; sponge; Theonella aff. mirabilis; (2-hydroxyethyl) dimethylsulfoxonium chloride;

D O I：

10.1016/S1096-4959(00)00316-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

(2-Hydroxyethyl) dimethylsulfoxonium chloride (1), the well-known causative agent of Dogger Bank Itch, has been isolated as a cytotoxic constituent from the marine sponge Theonella aff. mirabilis. The structure of I was determined by spectral and X-ray crystallographic analyses. (C) 2001 Elsevier Science Inc. All rights reserved.

引用

页码：27 / 30

页数：4

共 3 条

[1] Synthesis of tokaramide A, a cysteine protease inhibitor from marine sponge Theonella aff. mirabilis
Konno, Hiroyuki
Nosaka, Kazuto
Akaji, Kenichi
[J]. TETRAHEDRON, 2011, 67 (47) : 9067 - 9071
[2] Tokaramide A, a new cathepsin B inhibitor from the marine sponge Theonella aff. mirabilis
Fusetani, N
Fujita, M
Nakao, Y
Matsunaga, S
van Soest, RWM
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1999, 9 (24) : 3397 - 3402
[3] Bioactive marine metabolites.: Part 104.: Miraziridine A, a novel cysteine protease inhibitor from the marine sponge Theonella aff. mirabilis
Nakao, Y
Fujita, M
Warabi, K
Matsunaga, S
Fusetani, N
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (42) : 10462 - 10463

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