Synthesis of pyrazoloquinolines as gastric H+/K+-ATPase inhibitors

被引：0

作者：

Kalayanov, GD ^{[1
]}

Kang, SK ^{[1
]}

Cheon, HG ^{[1
]}

Lee, SG ^{[1
]}

Yum, EK ^{[1
]}

Kim, SS ^{[1
]}

Choi, JK ^{[1
]}

机构：

[1] Korea Res Inst Chem Technol, Taejon 305606, South Korea

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 1998年 / 19卷 / 06期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of l-aryl-1H-pyrazolo[4,3-c]quinolines and 2-aryl-2H-pyrazolo[4,3-c]quinolines are prepared by reacting 3-acyl-4-chloroquinolines in ethanol or 3-acyl-4(1H)-quinolone in acetic acid with appropriate hydrazines as possible anti-ulcer agents. A regiospecific synthesis of l-aryl-1H-pyrazolo[4,3-c]quinolines is also achieved. The central pyridine ring could be easily reduced by catalytic hydrogenation.

引用

页码：667 / 671

页数：5

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