Relevance of two distinct mechanisms for the antihyperglycaemic action of efaroxan in mice: antagonism to adrenergic α2-receptors versus closing of KATP-channels

被引:0
|
作者
Lehner, Z. [1 ]
Stadlbauer, K. [1 ]
Adorjan, I. [2 ]
Fenzl, A. [1 ]
Gruber, D. [1 ]
de Cillia, V. A. M. [1 ]
Frobel, K. [2 ]
Bauer, L. [2 ]
Rustenbeck, I. [3 ]
Luger, A. [1 ]
Fuernsinn, C. [1 ]
机构
[1] Med Univ Vienna, Dept Med 3, Div Endocrinol Metab, Vienna, Austria
[2] 55 Pharma Drug Discovery & Dev AG, Vienna, Austria
[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Pharmacol & Toxicol, Braunschweig, Germany
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D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
591
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收藏
页码:S243 / S243
页数:1
相关论文
共 2 条
  • [1] Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes?
    Z. Lehner
    K. Stadlbauer
    I. Adorjan
    I. Rustenbeck
    M. Belz
    A. Fenzl
    V. A. M. de Cillia
    D. Gruber
    L. Bauer
    K. Frobel
    B. Brunmair
    A. Luger
    C. Fürnsinn
    Diabetologia, 2012, 55 : 3071 - 3082
  • [2] Mechanisms of antihyperglycaemic action of efaroxan in mice: time for reappraisal of α2A-adrenergic antagonism in the treatment of type 2 diabetes?
    Lehner, Z.
    Stadlbauer, K.
    Adorjan, I.
    Rustenbeck, I.
    Belz, M.
    Fenzl, A.
    de Cillia, V. A. M.
    Gruber, D.
    Bauer, L.
    Frobel, K.
    Brunmair, B.
    Luger, A.
    Fuernsinn, C.
    DIABETOLOGIA, 2012, 55 (11) : 3071 - 3082