Is the progression of Huntington's disease determined by somatic CAG repeat instability?

被引:0
|
作者
Vatsavayai, SC [1 ]
Dallérac, GM [1 ]
Milner, AJ [1 ]
Cummings, DM [1 ]
Murphy, KPSJ [1 ]
Hirst, MC [1 ]
机构
[1] Open Univ, Milton Keynes MK7 6AA, Bucks, England
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [1] A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease
    Aldous, Sarah G.
    Smith, Edward J.
    Landles, Christian
    Osborne, Georgina F.
    Canibano-Pico, Maria
    Nita, Iulia M.
    Phillips, Jemima
    Zhang, Yongwei
    Jin, Bo
    Hirst, Marissa B.
    Benn, Caroline L.
    Bond, Brian C.
    Edelmann, Winfried
    Greene, Jonathan R.
    Bates, Gillian P.
    [J]. BRAIN, 2024, 147 (05) : 1784 - 1798
  • [2] Dynamics of somatic CAG instability in Huntington's disease
    Gonitel, R
    Woodman, B
    Sathasivam, K
    Bates, G
    Faull, R
    Detloff, P
    Lucas, J
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76
  • [3] CAG repeat length and clinical progression in Huntington's disease
    Ravina, B.
    Romer, M.
    Constantinescu, R.
    Biglan, K.
    Kieburtz, K.
    Shoulson, I.
    McDermott, M.
    [J]. MOVEMENT DISORDERS, 2006, 21 : S414 - S415
  • [4] Intergenerational CAG repeat instability is highly heritable in Huntington's disease
    Aziz, N. A.
    van Belzen, M. J.
    Roos, R. A. C.
    [J]. JOURNAL OF MEDICAL GENETICS, 2008, 45 (11) : 766 - 766
  • [5] Age, CAG repeat length, and clinical progression in Huntington's disease
    Rosenblatt, Adam
    Kumar, Brahma V.
    Mo, Alisa
    Welsh, Claire S.
    Margolis, Russell L.
    Ross, Christopher A.
    [J]. MOVEMENT DISORDERS, 2012, 27 (02) : 272 - 276
  • [6] The relationship between CAG repeat length and progression in Huntington's disease
    Ravina, Bernard
    Romer, Megan
    Constantinescu, Radu
    Biglan, Kevin
    Kieburtz, Karl
    Shoulson, Ira
    McDermott, Michael
    [J]. ANNALS OF NEUROLOGY, 2007, 62 : S40 - S40
  • [7] The effects of CAG repeat length on clinical progression in Huntington's disease
    Rosenblatt, A
    Abbott, MH
    Gourley, LM
    Margolis, RL
    Brandt, J
    Ross, CA
    Liang, KY
    Zhou, H
    [J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76
  • [8] Somatic CAG Repeat Stability in a Transgenic Sheep Model of Huntington's Disease
    Handley, Renee R.
    Reid, Suzanne J.
    Burch, Zoe
    Jacobsen, Jessie C.
    Gillis, Tammy
    Correia, Kevin
    Rudiger, Skye R.
    McLaughlin, Clive J.
    Bawden, C. Simon
    MacDonald, Marcy E.
    Wheeler, Vanessa C.
    Snell, Russell G.
    [J]. JOURNAL OF HUNTINGTONS DISEASE, 2024, 13 (01) : 33 - 40
  • [9] SOMATIC EXPANSION OF THE (CAG)(N) REPEAT IN HUNTINGTON DISEASE BRAINS
    DEROOIJ, KE
    GANS, PAMD
    ROOS, RAC
    VANOMMEN, GJB
    DENDUNNEN, JT
    [J]. HUMAN GENETICS, 1995, 95 (03) : 270 - 274
  • [10] The relationship between CAG repeat length and clinical progression in Huntington's disease
    Ravina, Bernard
    Romer, Megan
    Constantinescu, Radu
    Biglan, Kevin
    Brocht, Alicia
    Kieburtz, Karl
    Shoulson, Ira
    McDermott, Michael P.
    [J]. MOVEMENT DISORDERS, 2008, 23 (09) : 1223 - 1227