IN-VIVO INTRAVASCULAR INTERVENTION WITH PARYLENE MICRO ELECTRODE TO DIAGNOSE RUPTURE-PRONE ATHEROSCLEROTIC PLAQUE USING ELECTRICAL IMPEDANCE SPECTROSCOPY

被引:0
|
作者
Luo, Yuan [1 ]
Zhang, Xiaoxiao [1 ]
Packard, Rene [2 ]
Li, Rongsong [2 ]
Hsiai, Tzung [2 ]
Liu, Yang [1 ]
Tai, Yu-Chong [1 ]
机构
[1] CALTECH, Micro Machining Lab, Pasadena, CA 91125 USA
[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
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中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
It is of great clinical interest to have easy and reliable diagnostic techniques to localize and identify vulnerable plaques. Here, an in-vivo, catheter-integrated and balloon mounted Parylene-C micro electrode impedance sensor was developed for intra-vascular interrogation of atherosclerotic vulnerable plaques using Electrical Impedance spectroscopy (EIS). Successful in vivo experiments of the EIS device were demonstrated using high-fat-dieted New Zealand rabbits. The results showed that electrical impedance spectroscopy (EIS) with micro parylene electrodes is promising to distinguish unstable plaques.
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页码:307 / 310
页数:4
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