Introduction. Living kidney donation (LKD) is one of the most used alternatives in the field of organ transplantation. Objective. Analyze the attitude toward LKD among the population of Havana, Cuba. Methods. Population under study. Population resident in Havana, Cuba. Inclusion criteria. Sample of population over 15 years stratified by age and sex. Instrument. Validated questionnaire of attitude toward donation and transplant "PCID-DVR-Rios," self-administered and anonymously filled out. Statistics. chi(2), Student t test, and a logistic regression analysis. Results. A total of 920 respondents have been included in the study. A total of 85.5% (n = 787) are in favor of the related LKD. In our study, 26.5% (n = 244) would remain in favor of unrelated LKD. Regarding the related LKD, the following variables remain independent in the multivariate analysis: 1. having studies (odds ratio [OR] = 3.649; P = .018); 2. attitude toward cadaveric organ donation (OR = 8.547; P < .001); 3. religion (OR = 4.385; P = .001); 4. opinion of the couple (OR = 4.672; P = .028); and 5. risk with living donation (OR = 10.989; P = .003). Conclusions. The population of Havana has a very favorable attitude toward related LKD. Only a quarter of respondents are in favor of unrelated LKD.