Heat shock protein-based novel immunotherapies

被引:26
|
作者
Srivastava, PK [1 ]
机构
[1] Univ Connecticut, Sch Med, Ctr Immunotherapy Canc & Infect Dis MC1601, Farmington, CT 06030 USA
关键词
D O I
10.1358/dnp.2000.13.9.858479
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The ability of heat shock proteins to chaperone peptides, including antigenic peptides; to interact with antigen-presenting cells through a receptor; to stimulate antigen-presenting cells to secrete inflammatory cytokines; and to mediate maturation of dendritic cells makes them a unique starting point for generation of immune responses. These properties also permit the utilization of heat shock proteins for development of a new generation of prophylactic and therapeutic vaccines against cancers and infectious diseases. (C) 2000 Prous Science. All rights reserved.
引用
收藏
页码:517 / 522
页数:6
相关论文
共 50 条
  • [1] Heat shock protein-based cancer vaccines
    Lee, Kelvin P.
    Raez, Luis E.
    Podack, Eckhard R.
    [J]. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 2006, 20 (03) : 637 - 659
  • [2] Heat shock protein-based immunotherapy of cancer
    Truneh, A
    [J]. JOURNAL OF IMMUNOTHERAPY, 2004, 27 (06) : S56 - S56
  • [3] Heat shock protein-based therapy for sphingolipidoses
    Kirkegaard, Thomas
    Gray, James
    Priestman, David
    Wallom, Kerri-Lee
    Petersen, Nikolaj
    Ingemann, Linda
    Bornaes, Claus
    Drndarski, Svetlana
    Klein, Alexander
    Jorgensen, Signe H.
    Atkins, Jennifer
    Olsen, Ole D.
    Smith, David A.
    Hinsby, Anders
    Arenz, Christoph
    Begley, David
    Jaattela, Marja
    Platt, Frances M.
    [J]. MOLECULAR GENETICS AND METABOLISM, 2017, 120 (1-2) : S75 - S75
  • [4] Recent advances in heat shock protein-based cancer vaccines
    Hao-Hao Wang
    [J]. Hepatobiliary & Pancreatic Diseases International, 2006, (01) : 22 - 27
  • [5] Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses
    Kirkegaard, Thomas
    Gray, James
    Priestman, David A.
    Wallom, Kerri-Lee
    Atkins, Jennifer
    Olsen, Ole Dines
    Klein, Alexander
    Drndarski, Svetlana
    Petersen, Nikolaj H. T.
    Ingemann, Linda
    Smith, David A.
    Morris, Lauren
    Bornaes, Claus
    Jorgensen, Signe Humle
    Williams, Ian
    Hinsby, Anders
    Arenz, Christoph
    Begley, David
    Jaattela, Marja
    Platt, Frances M.
    [J]. SCIENCE TRANSLATIONAL MEDICINE, 2016, 8 (355)
  • [6] Antigen Cross-Presentation and Heat Shock Protein-Based Vaccines
    Katerina Zachova
    Michal Krupka
    Milan Raska
    [J]. Archivum Immunologiae et Therapiae Experimentalis, 2016, 64 : 1 - 18
  • [7] Heat-shock protein-based vaccines for cancer and infectious disease
    Binder, Robert J.
    [J]. EXPERT REVIEW OF VACCINES, 2008, 7 (03) : 383 - 393
  • [8] Antigen Cross-Presentation and Heat Shock Protein-Based Vaccines
    Zachova, Katerina
    Krupka, Michal
    Raska, Milan
    [J]. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2016, 64 (01) : 1 - 18
  • [9] Heat Shock Protein-Peptide and HSP-Based Immunotherapies for the Treatment of Cancer
    Shevtsov, Maxim
    Multhoff, Gabriele
    [J]. FRONTIERS IN IMMUNOLOGY, 2016, 7
  • [10] Heat shock fusion protein-based immunotherapy for treatment of cervical intraepithelial neoplasia III
    Einstein, Mark H.
    Kadish, Anna S.
    Burk, Robert D.
    Kim, Mimi Y.
    Wadler, Scott
    Strelcher, Howard
    Goldberg, Gary L.
    Runowicz, Carolyn D.
    [J]. GYNECOLOGIC ONCOLOGY, 2007, 106 (03) : 453 - 460