Long-term monitoring of gait in Parkinson's disease

被引：142
|
作者：
Moore, Steven T.
MacDougall, Hamish G.
Gracies, Jean-Michel
Cohen, Helen S.
Ondo, William G.
机构：
[1] Mt Sinai Sch Med, Dept Neurol, New York, NY 10029 USA
[2] Baylor Coll Med, Bobby R Alford Dept Otolaryngol Head & Neck Surg, Houston, TX 77030 USA
[3] Baylor Coll Med, Dept Neurol, Houston, TX 77030 USA
来源：
GAIT & POSTURE | 2007年 / 26卷 / 02期
关键词：
stride length; levodopa; parkinsonian; locomotion; accelerometer;
D O I：
10.1016/j.gaitpost.2006.09.011
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A new system for long-term monitoring of gait in Parkinson's disease (PD) has been developed and validated. The characteristics of every stride taken over 10-h epochs were acquired using a lightweight ankle-mounted sensor array that transmitted data wirelessly to a small pocket PC at a rate of 100 Hz. Stride was calculated from the vertical linear acceleration and pitch angular velocity of the leg with an accuracy of 5 cm. Results from PD patients (5) demonstrate the effectiveness of long-term monitoring of gait in a natural environment. The small, variable stride length characteristic of Parkinsonian gait, and fluctuations of efficacy associated with levodopa therapy, such as delayed onset, wearing off, and the 'off/on' effect, could reliably be detected from long-term changes in stride length. (c) 2006 Elsevier B.V. All rights reserved.
引用
收藏
页码：200 / 207
页数：8
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