Boron neutron capture therapy for glioblastoma: Is it worth pursuing?

被引：6
|
作者：
Linz, Ute [1 ]
机构：
[1] Forschungszentrum Julich, D-52425 Julich, Germany
来源：
TECHNOLOGY IN CANCER RESEARCH & TREATMENT | 2008年 / 7卷 / 01期
关键词：
BNCT; brain tumors; glioblastoma; radiotherapy;
D O I：
10.1177/153303460800700110
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Presently glioblastomas are incurable brain tumors. The prospect of treating this deadly disease has been the major justification for the current programs of boron neutron capture therapy (BNCT) throughout the world. However, based on pharmacological and cell biological considerations, it is improbable that BNCT will ever be an effective therapy for this tumor. Indeed, a review of the published literature over the last 50 years fails to provide justification for developing BNCT past its present experimental stage.
引用
收藏
页码：83 / 88
页数：6
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