Advances in Hepatitis C Treatment: At the Crossroads

被引：1

作者：

Lam, Jerika T. ^{[1
]}

Yamaki, Jason ^{[2
]}

Kayali, Zeid ^{[3
]}

机构：

[1] Chapman Univ, Sch Pharm, HIV Infect Dis, Irvine, CA 92618 USA

[2] Chapman Univ, Sch Pharm, Irvine, CA USA

[3] Inland Empire Liver Fdn, Rialto, CA USA

来源：

JNP-JOURNAL FOR NURSE PRACTITIONERS | 2015年 / 11卷 / 07期

关键词：

direct acting antivirals; hepatitis C virus; interferon free regimens; sustained virologic response; TREATMENT-NAIVE PATIENTS; VIRUS GENOTYPE 1; INTERFERON-ALPHA; 2A; PEGYLATED INTERFERON; CHRONIC HCV; PLUS RIBAVIRIN; DOUBLE-BLIND; SOFOSBUVIR; INFECTION; SIMEPREVIR;

D O I：

10.1016/j.nurpra.2015.04.029

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Chronic hepatitis C virus (HCV) infection is a serious public health problem. Globally over 170 million persons are infected and suffer from HCV infection, cirrhosis, and hepatocellular carcinoma: HCV infection among the leading causes of death in the United: States. Recently; there have been newer, direct-acting antiviral agents approved by the US Food and Drug Administration for treatment of HCV for genotypes 1-4. The air of this study is to evaluate the clinical efficacy, pharmacologic properties, and safety profiles from clinical trials and the costs associated with the new antiviral regimens, including sofosbuvir, simeprevir and ledipasvir/sofosbuvir.

引用

页码：669 / 679

页数：11

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