CD40 ligand rescues chronic lymphocytic leukemia (CLL) cells from spontaneous apoptosis and mediates resistance to Fas ligand and fludarabine.

被引:0
|
作者
Younes, A
Snell, V
Consoli, U
Clodi, K
Thomas, EK
Andreeff, M
机构
[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT HEMATOL,HOUSTON,TX
[2] IMMUNEX CORP,SEATTLE,WA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:931 / 931
页数:1
相关论文
共 50 条
  • [1] Fas-ligand and TRAIL are synergistic in inducing apoptosis of chronic lymphocytic leukemia cells following CD40 ligation.
    Dicker, F
    Kipps, TJ
    BLOOD, 2002, 100 (11) : 378A - 378A
  • [2] Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells
    Romano, MF
    Lamberti, A
    Tassone, P
    Alfinito, F
    Costantini, S
    Chiurazzi, F
    Defrance, T
    Bonelli, P
    Tuccillo, F
    Turco, MC
    Venuta, S
    BLOOD, 1998, 92 (03) : 990 - 995
  • [3] BCL-2, Bcl-x(L) may confer resistance to Fas/Fas ligand mediated apoptosis in chronic lymphocytic leukemia (CLL) cells
    ElTounsi, I
    Zhao, S
    Younes, A
    Consoli, U
    Thomas, E
    Lynch, D
    Andreeff, M
    BLOOD, 1995, 86 (10) : 1372 - 1372
  • [4] Fas-ligand (CD178) and TRAIL synergistically induce apoptosis of CD40-activated chronic lymphocytic leukemia B cells
    Dicker, F
    Kater, AP
    Fukuda, T
    Kipps, TJ
    BLOOD, 2005, 105 (08) : 3193 - 3198
  • [5] STUDY OF CD40 LIGAND EXPRESSION IN B-CELL CHRONIC LYMPHOCYTIC-LEUKEMIA
    BRUGNONI, D
    ROSSI, G
    TUCCI, A
    CATTANEO, R
    AIRO, P
    HAEMATOLOGICA, 1995, 80 (05) : 440 - 442
  • [6] Acquired CD40 ligand deficiency in patients with B cell chronic lymphocytic leukemia.
    Cantwell, MJ
    Hua, T
    Pappas, J
    Kipps, TJ
    BLOOD, 1996, 88 (10) : 1173 - 1173
  • [7] The Role of CD137 and Its Ligand in Chronic Lymphocytic Leukemia (CLL)
    Baessler, Tina
    Buechele, Corina
    Krusch, Matthias
    Schmiedel, Benjamin J.
    Kanz, Lothar
    Salih, Helmut R.
    BLOOD, 2008, 112 (11) : 1073 - 1073
  • [8] CD40 ligand-induced apoptosis is Fas-independent in human multiple myeloma cells
    Tong, AW
    Seamour, B
    Chen, J
    Su, D
    Ordonez, G
    Frase, L
    Netto, G
    Stone, MJ
    LEUKEMIA & LYMPHOMA, 2000, 36 (5-6) : 543 - 558
  • [9] Induction of Fas-independent apoptosis in human multiple myeloma cells by CD40 ligand.
    Tong, AW
    Chen, J
    Seymour, B
    Frase, L
    Netto, G
    Stone, MJ
    BLOOD, 1998, 92 (10) : 638A - 638A
  • [10] Ligation of CD40 on B-cell chronic lymphocytic leukemia (B-CLL) cells promotes increased survival but does not impair fludarabine induced apoptosis.
    Grdisa, M
    Tang, RP
    Delmer, A
    Levy, V
    Gribben, JG
    Ajchenbaum-Cymbalista, F
    BLOOD, 2000, 96 (11) : 159A - 159A