SEOM clinical guidelines for hereditary cancer

被引：14

作者：

Grana, Begona ^{[1
,2
]}

Lastra, Enrique ^{[3
]}

Llort, Gemma ^{[4
]}

Brunet, Joan ^{[5
]}

Isla, Dolores ^{[6
]}

机构：

[1] VHIO, Dept Med Oncol, High Risk & Canc Prevent Unit, ES-08035 Barcelona, Spain

[2] Marcide Hosp, Ferrol Healthcare Area, La Coruna, Spain

[3] Gen Yague Hosp, Med Oncol Sect, Genet Counselling Unit, Burgos, Spain

[4] Valles Inst Oncol, Genet Counselling Unit, Barcelona, Spain

[5] ICO, Hereditary Canc Program, Dept Med Oncol, Girona, Spain

[6] Lozano Blesa Hosp, Dept Med Oncol, Zaragoza, Spain

来源：

CLINICAL & TRANSLATIONAL ONCOLOGY | 2011年 / 13卷 / 08期

关键词：

Hereditary cancer; BRCA1; BRCA2; Lynch syndrome; BRCA2 MUTATION CARRIERS; NONPOLYPOSIS COLORECTAL-CANCER; OVARIAN-CANCER; LYNCH-SYNDROME; BREAST-CANCER; SALPINGO-OOPHORECTOMY; INHERITED MUTATIONS; YOUNG-WOMEN; RISK; FAMILIES;

D O I：

10.1007/s12094-011-0701-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Research in genetics has facilitated the identification of highly penetrant genes responsible for a large number of diseases. In the oncology field, genetic counselling and gene testing are focused on the two most common syndromes in familial cancer: hereditary breast and ovarian cancer syndrome (HBOC) and hereditary non-polyposis colorectal cancer or Lynch syndrome (LS). The objective of this guideline in hereditary cancer is to summarise the current state of knowledge and make recommendations in the areas of diagnosis, prevention and treatment of hereditary cancer.

引用

页码：580 / 586

页数：7

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