Efficacy of inhaled CPZEN-45 in treating tuberculosis in the guinea pig

被引:0
|
作者
Young, Ellen F. [1 ]
Durham, Phillip G. [2 ]
Perkowski, Ellen F. [1 ]
Malik, Seidu [1 ]
Hickey, Anthony J. [2 ]
Braunstein, Miriam [1 ]
机构
[1] Univ North Carolina Chapel Hill, Dept Microbiol & Immunol, Sch Med, Chapel Hill, NC 27599 USA
[2] RTI Int, Res Triangle Pk, NC 27709 USA
关键词
CPZEN-45; Antibiotic; Aerosol; Tuberculosis; Guinea pig; EXPERIMENTAL AIRBORNE TUBERCULOSIS; DRUG; MODEL;
D O I
10.1016/j.tube.20zz.102207
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [1] A Spray-Dried Combination of Capreomycin and CPZEN-45 for Inhaled Tuberculosis Therapy
    Pitner, Ragan A.
    Durham, Phillip G.
    Stewart, Ian E.
    Reed, Steven G.
    Cassell, Gail H.
    Hickey, Anthony J.
    Carter, Darrick
    [J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 108 (10) : 3302 - 3311
  • [2] The Pharmacokinetics of CPZEN-45, a Novel Anti-Tuberculosis Drug, in Guinea Pigs
    Garcia-Contreras, Lucila
    Hanif, Shumaila Nida Muhammad
    Ibrahim, Mariam
    Durham, Phillip
    Hickey, Anthony J.
    [J]. PHARMACEUTICS, 2023, 15 (12)
  • [3] PHARMACOKINETICS OF CPZEN-45, A NOVEL ANTI-TUBERCULOSIS DRUG IN MALE GUINEA PIGS
    Hanif, S. N. M.
    Durham, P.
    Raghuvanshi, D.
    Hickey, A. J.
    Contreras, L. Garcia
    [J]. JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2013, 26 (02) : A18 - A18
  • [4] Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment
    Ian E. Stewart
    Phillip G. Durham
    Jacob M. Sittenauer
    Aranza P. Barreda
    Grayson W. Stowell
    Carmella Moody
    Jeffery B. Mecham
    Catherine Simpson
    Sharon Daily
    Sara E. Maloney
    Mark D. Williams
    Diana Severynse-Stevens
    Anthony J. Hickey
    [J]. Pharmaceutical Research, 2022, 39 : 3359 - 3370
  • [5] Optimization and Scale Up of Spray Dried CPZEN-45 Aerosol Powders for Inhaled Tuberculosis Treatment
    Stewart, Ian E.
    Durham, Phillip G.
    Sittenauer, Jacob M.
    Barreda, Aranza P.
    Stowell, Grayson W.
    Moody, Carmella
    Mecham, Jeffery B.
    Simpson, Catherine
    Daily, Sharon
    Maloney, Sara E.
    Williams, Mark D.
    Severynse-Stevens, Diana
    Hickey, Anthony J.
    [J]. PHARMACEUTICAL RESEARCH, 2022, 39 (12) : 3359 - 3370
  • [6] Catalytic asymmetric synthesis of CPZEN-45
    Takeuchi, Toshifumi
    Abe, Hikaru
    Watanabe, Takumi
    Shibasaki, Masakatsu
    [J]. TETRAHEDRON LETTERS, 2016, 57 (26) : 2901 - 2904
  • [7] Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis
    Salomon, Johanna J.
    Galeron, Pauline
    Schulte, Nanette
    Morow, Paul R.
    Severynse-Stevens, Diana
    Huwer, Hanno
    Daum, Nicole
    Lehr, Claus-Michael
    Hickey, Anthony J.
    Ehrhardt, Carsten
    [J]. THERAPEUTIC DELIVERY, 2013, 4 (08) : 915 - 923
  • [8] DEVELOPMENT OF AN HPLC METHOD TO DETERMINE CPZEN-45 IN BIOLOGICAL MATRICES
    Hanif, S. N. M.
    Hickey, A. J.
    Contreras, L. Garcia
    [J]. JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY, 2013, 26 (02) : A20 - A21
  • [9] Synthesis and biological activity of analogs of CPZEN-45, a novel antituberculosis drug
    Ishizaki, Yoshimasa
    Takahashi, Yoshiaki
    Kimura, Tomoyuki
    Inoue, Michitaka
    Hayashi, Chigusa
    Igarashi, Masayuki
    [J]. JOURNAL OF ANTIBIOTICS, 2019, 72 (12): : 970 - 980
  • [10] Synthesis and biological activity of analogs of CPZEN-45, a novel antituberculosis drug
    Yoshimasa Ishizaki
    Yoshiaki Takahashi
    Tomoyuki Kimura
    Michitaka Inoue
    Chigusa Hayashi
    Masayuki Igarashi
    [J]. The Journal of Antibiotics, 2019, 72 : 970 - 980