Objectives: To develop and test the reliability of a modified version of the OMERACT rheumatoid arthritis magnetic resonance imaging score ( RAMRIS) for erosions using extremity MRI ( eMRI) with reduced field of view ( RAMRIS-RV). Methods: Using a MagneVu 0.2 T machine, the preliminary RAMRIS-RV assessed erosions in metacarpophalangeal ( MCP) joints 2-3, bases of metacarpal ( MC) 2-5, and all wrist bones excluding base MC 1, pisiform and trapezium. T1 weighted images of >= 500 MCP and wrist bony sites from a mixed severity RA and control cohort were evaluated. An inter-reader reliability study evaluating 300 wrist and 160 MCP bony sites was then performed. Results: Mean per cent exact ( and close) agreement results were as follows: MCP proximal sites 83.5 ( 96.2), MCP distal 54.4 ( 77.2), bases MC 2-4 85.2 ( 96.7), carpal bones 79.0 ( 92.1), distal radius/ulna 66.4 ( 87.8). The base of MCP 5 was visualised in <= 50% cases ( 13/25) and was removed from the final RAMRIS-RV. Conclusions: The RAMRIS-RV is a practical tool that can be used with eMRI with a reduced field of view. This study shows excellent inter-reader reliability for erosion assessment, albeit in a reduced number of bony sites.
机构:
USAF, Wilford Hall Med Ctr, Dept Radiol, Lackland AFB, TX USA
Univ Massachusetts, Dept Phys, Lowell, MA USAHarvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA
Aljallad, Mohammed H.
Yuan, Jing
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Chinese Univ Hong Kong, Dept Imaging & Intervent Radiol, Shatin, Hong Kong, Peoples R ChinaHarvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA
Yuan, Jing
Pilatou, Magdalini C.
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Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USAHarvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA
Pilatou, Magdalini C.
McDannold, Nathan J.
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Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USAHarvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA
McDannold, Nathan J.
Panych, Lawrence P.
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Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USAHarvard Univ, Brigham & Womens Hosp, Sch Med, Dept Radiol, Boston, MA 02115 USA
机构:
Univ Calif San Francisco, Radiol Med & Orthopaed, San Francisco, CA 94143 USA
Synarc Inc, San Francisco, CA USACopenhagen Univ Hosp Glostrup, Dept Rheumatol, Rheumatol, Copenhagen, Denmark