Gas chromatographic enantiomer separation of mandelates and its analogs on permethylated cyclodextrin chiral stationary phases

被引：0

作者：

Nie, MY ^{[1
]}

Zhou, LM ^{[1
]}

Wang, QH ^{[1
]}

Zhu, DQ ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116012, Peoples R China

来源：

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY | 2000年 / 28卷 / 11期

关键词：

enantiomer separation; cyclodextrin derivatives; alpha-hydroxycarboxylic acids; enthalpyentropy compensation;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Gas chromatographic enantionmer separation of mandelates and its analogs was investigated on permethylated beta -cyclodextrin (PMBCD) and permethylated gamma -cyclodextrin (PMGCD) chiral stationary phases(CSPs). The compounds investigated included methyl and ethyl mandelates, methyl and ethyl alpha -methoxymandelates, methyl and ethyl 3-phenylacetates, ethyl 2-hydroxy-4-phenyl butyrate. AU the compounds studied can be chirally separated to baseline an PMBCD CSPs, hut no enantiomer separation was observed on PMGCD CSPs for all the tested compounds, Some thermodynamic data were evaluated and used to delve the mechanism of chiral recognition between permethylated cyclodextrins and mandelates and their analogs.

引用

页码：1366 / 1370

页数：5

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