Implementation of Good Laboratory Practices (GLP) in basic scientific research: Translating the concept beyond regulatory compliance

被引:12
|
作者
Jena, G. B. [1 ]
Chavan, Sapana [1 ]
机构
[1] Natl Inst Pharmaceut Educ & Res, Facil Risk Assessment & Intervent Studies, Dept Pharmacol & Toxicol, Sect 67, Sas Nagar 160062, Punjab, India
关键词
Good laboratory practices; Regulatory toxicology; Research in basic science; Reliability; Reproducibility; SAFETY PHARMACOLOGY; DIAGNOSTIC LABORATORIES; PRECLINICAL RESEARCH; QUALITY-ASSURANCE; REQUIREMENTS; TOXICOLOGY; REPRODUCIBILITY; PRINCIPLES; CHEMICALS; DECISIONS;
D O I
10.1016/j.yrtph.2017.07.010
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
The principles of Good Laboratory Practices (GLPs) are mainly intended for the laboratories performing studies for regulatory compliances. However, today GLP can be applied to broad disciplines of science to cater to the needs of the experimental objectives, generation of quality data and assay reproducibility. Considering its significance, it can now be applied in academics; industries as well as government set ups throughout the world. GLP is the best way to promote the reliability, reproducibility of the test data and hence facilitates the international acceptability. Now it is high time to translate and implement the concept of GLP beyond regulatory studies. Thus, it can pave the way for better understanding of scientific problems and help to maintain a good human and environmental health. Through this review, we have made an attempt to explore the uses of GLP principles in different fields of science and its acceptability as well as looking for its future perspectives. (C) 2017 Elsevier Inc. All rights reserved.
引用
收藏
页码:20 / 25
页数:6
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