Exercise as a Moderator of Persistent Neuroendocrine Symptoms of COVID-19

被引：16

作者：

Rebello, Candida J. ^{[1
]}

Axelrod, Christopher L. ^{[1
]}

Reynolds, Charles F., III ^{[2
]}

Greenway, Frank L. ^{[1
]}

Kirwan, John P. ^{[1
]}

机构：

[1] Pennington Biomed Res Ctr, Baton Rouge, LA USA

[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15260 USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2022年 / 50卷 / 02期

基金：

美国国家卫生研究院;

关键词：

exercise; COVID-19; psychological stress; immune dysregulation; hyperinflammation; TNF-ALPHA; SKELETAL-MUSCLE; DEPRESSIVE SYMPTOMS; INSULIN SENSITIVITY; PHYSICAL-ACTIVITY; RANDOMIZED-TRIAL; GLYCEMIC CONTROL; DOUBLE-BLIND; TYPE-2; INTERLEUKIN-6;

D O I：

10.1249/JES.0000000000000284

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Precipitated by chronic psychological stress, immune system dysregulation, and a hyperinflammatory state, the sequelae of postacute COVID-19 (long COVID) include depression and new-onset diabetes. We hypothesize that exercise counters the neuropsychiatric and endocrine sequelae of long COVID by inducing the release of circulating factors that mediate the anti-inflammatory response, support brain homeostasis, and increase insulin sensitivity.

引用

页码：65 / 72

页数：8

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