Ritlecitinib (PF-06651600), an oral JAK3/TEC inhibitor, shows efficacy in patients with active nonsegmental vitiligo and either a lighter or darker Fitzpatrick skin type: Results from a phase 2b, randomized, dose-ranging study with an extension period

被引:0
|
作者
Peeva, Elena [1 ]
Yamaguchi, Yuji [1 ]
King, Brett [2 ]
机构
[1] Pfizer Inc, New York, NY USA
[2] Yale Sch Med, New Haven, CT USA
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
33304
引用
收藏
页码:AB105 / AB105
页数:1
相关论文
共 12 条
  • [1] Ritlecitinib (PF-06651600), an oral JAK3/TEC inhibitor, stabilizes active lesions and promotes repigmentation of stable lesions in patients with active nonsegmental vitiligo: Results from a phase 2b, randomized, placebo-controlled, dose-ranging study
    Yamaguchi, Yuji
    Peeva, Elena
    Shore, Ronald
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 87 (03) : AB105 - AB105
  • [2] Clinical efficacy of the oral JAK3/TEC inhibitor ritlecitinib (PF-06651600) and patients' perception of improvement in alopecia areata: Results from the ALLEGRO Phase 2b/3 trial
    Guttman-Yassky, E.
    Ito, T.
    Jabbari, A.
    Mackay-Wiggan, J.
    Lejeune, A.
    Wolk, R.
    Wajsbrot, D.
    Zwillich, S. H.
    EXPERIMENTAL DERMATOLOGY, 2021, 30 : 20 - 20
  • [3] Efficacy of the oral JAK3/TEC inhibitor ritlecitinib (PF-06651600) in patients with alopecia areata over 48 weeks: Results from the ALLEGRO Phase 2b/3 randomized, double-blind, placebocontrolled trial
    Mesinkovska, Natasha
    Shapiro, Jerry
    King, Brett
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 87 (03) : AB54 - AB54
  • [4] Safety of the oral JAK3/TEC inhibitor ritlecitinib (PF-06651600) in patients with alopecia areata: Results from the ALLEGRO phase 2b/3, randomized, double-blind, placebo-controlled trial
    King, Brett
    Szepietowski, Jacek C.
    Farrant, Paul
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 87 (03) : AB106 - AB106
  • [5] Efficacy and safety of the oral JAK3/TEC inhibitor ritlecitinib in adolescents with alopecia areata: Results from the ALLEGRO Phase 2b/3 randomized, double-blind, placebo-controlled trial
    Hordinsky, Maria K.
    Hebert, Adelaide
    Gooderham, Melinda
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2022, 87 (03) : AB51 - AB51
  • [6] A Phase 2b dose-ranging trial of baricitinib, an oral JAM 1/JAK 2 inhibitor, in patients with moderate-to-severe psoriasis: Results from the randomized withdrawal and re-treatment periods
    Papp, Kim
    Menter, Alan
    Raman, Mani
    Janes, Jonathan
    Disch, Damon
    Macias, William
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2015, 135 : S7 - S7
  • [7] Filgotinib (GLPG0634), an Oral JAK1 Selective Inhibitor Is Effective As Monotherapy in Patients with Active Rheumatoid Arthritis: Results from a Phase 2B Dose Ranging Study
    Kavanaugh, Arthur
    Ponce, Lucia
    Cseuz, Regina
    Reshetko, Olga
    Stanislavchuk, Mykola A.
    Greenwald, Maria
    Van der Aa, Annegret
    Vanhoutte, Frederic
    Tasset, Chantal
    Harrison, Pille
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [8] Filgotinib (GLPG0634), an Oral JAK1 Selective Inhibitor Is Effective in Combination with Methotrexate in Patients with Active Rheumatoid Arthritis: Results from a Phase 2B Dose Ranging Study
    Westhovens, R.
    Alten, Rieke
    Pavlova, Dace
    Enriquez-Sosa, Favio
    Mazur, Minodora
    Greenwald, Maria
    Van der Aa, Annegret
    Vanhoutte, Frederic
    Tasset, Chantal
    Harrison, Pille
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [9] Efficacy and safety of ritlecitinib (PF06651600) in patients with alopecia areata and at least 50% scalp hair loss: results from the international ALLEGRO phase 2b/3 randomized, double-blind, placebo-controlled study (NCT03732807)
    King, Brett
    Zhang, Xingqi
    Gubelin, Walter
    Szepietowski, Jacek
    Shapiro, Jerry
    Lynde, Charles
    Mesinkovska, Natasha
    Zwillich, Samuel
    Napatalung, Lynne
    Wajsbrot, Dalia
    Fayyad, Rana
    Freyman, Amy
    Mitra, Debanjali
    Purohit, Vivek
    Sinclair, Rodney
    Wolk, Robert
    JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2023, 21 : 125 - 125
  • [10] FILGOTINIB (GLPG0634), AN ORAL JAK1 SELECTIVE INHIBITOR IS EFFECTIVE AS MONOTHERAPY IN PATIENTS WITH ACTIVE RHEUMATOID ARTHRITIS: RESULTS FROM A 24-WEEK PHASE 2B DOSE RANGING STUDY
    Kavanaugh, A.
    Ponce, L.
    Cseuz, R.
    Reshetko, O.
    Stanislavchuk, M.
    Greenwald, M.
    Van der Aa, A.
    Vanhoutte, F.
    Tasset, C.
    Harrison, P.
    ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 : 247 - 247