Risks in new drug development: Approval success rates for investigational drugs

被引：298
|
作者：
DiMasi, JA [1 ]
机构：
[1] Tufts Univ, Tufts Ctr Study Drug Dev, Boston, MA 02111 USA
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2001年 / 69卷 / 05期
关键词：
D O I：
10.1067/mcp.2001.115446
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：297 / 307
页数：11
相关论文
共 50 条
  • [1] Trends in Risks Associated With New Drug Development: Success Rates for Investigational Drugs
    DiMasi, J. A.
    Feldman, L.
    Seckler, A.
    Wilson, A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2010, 87 (03) : 272 - 277
  • [2] Clinical Approval Success Rates for Investigational Cancer Drugs
    DiMasi, J. A.
    Reichert, J. M.
    Feldman, L.
    Malins, A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2013, 94 (03) : 329 - 335
  • [3] Clinical development success rates for investigational drugs
    Hay, Michael
    Thomas, David W.
    Craighead, John L.
    Economides, Celia
    Rosenthal, Jesse
    NATURE BIOTECHNOLOGY, 2014, 32 (01) : 40 - 51
  • [4] Clinical development success rates for investigational drugs
    Michael Hay
    David W Thomas
    John L Craighead
    Celia Economides
    Jesse Rosenthal
    Nature Biotechnology, 2014, 32 : 40 - 51
  • [5] Development Times and Approval Success Rates for Drugs to Treat Infectious Diseases
    DiMasi, Joseph A.
    Florez, Maria, I
    Stergiopoulos, Stella
    Pena, Yaritza
    Smith, Zachary
    Wilkinson, Michael
    Getz, Kenneth A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2020, 107 (02) : 324 - 332
  • [6] DEVELOPMENT AND INTRODUCTION OF NEW CARDIOVASCULAR DRUGS - DRUG APPROVAL PROCESS
    GOLDBERG, LI
    PELTIER, AC
    CROUT, JR
    BELTON, ED
    CHRISTEN.CN
    COVINO, B
    KOHLSTAE.KG
    SAUNDERS, DE
    SCHIFFRI.MJ
    AMERICAN JOURNAL OF CARDIOLOGY, 1974, 34 (04): : 485 - 486
  • [7] Success rates for product development strategies in new drug development
    Dahlin, E.
    Nelson, G. M.
    Haynes, M.
    Sargeant, F.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2016, 41 (02) : 198 - 202
  • [8] Drug Registries and Approval of Drugs: Promises, Placebo, or a Real Success?
    Jonker, Carla J.
    Kwa, Marcel S. G.
    van den Berg, H. Marijke
    Hoes, Arno W.
    Mol, Peter G. M.
    CLINICAL THERAPEUTICS, 2018, 40 (05) : 768 - 773
  • [9] Finding New Drugs for Infectious Diseases: Development Times and Success Rates
    van der Graaf, Piet H.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2020, 107 (02) : 305 - 307
  • [10] Basic requirements for investigational new drug and new drug application approval for an antioxidant compound in cardiovascular disease
    Witztum, JL
    AMERICAN JOURNAL OF CARDIOLOGY, 1998, 81 (8A): : 50F - 51F
12345