RNase activity of single chain ribosome-inactivating proteins.

被引：0
|
作者：
Chen, H
Hua, L
Wang, Y
Zhao, K
Yan, MG
Dong, YC
机构：
[1] ACAD SINICA, INST BIOPHYS, BEIJING 100101, PEOPLES R CHINA
[2] UNIV SCI & TECHNOL CHINA, GRAD SCH, BEIJING 100039, PEOPLES R CHINA
来源：
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS | 1996年 / 23卷 / 05期
关键词：
ribosome-inactivating protein; ribonuclease activity; trichosanthin;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Five purified preparations of ribosome-inactivating proteins ( RIPs), trichosanthin, momorcharin, saporin, luffin and gelonin were shown to exhibit ribonuclease activity, under pH 5.0, with celery 4.5 S RNA as substrates. The autoradiography showed that different RIPS had different base specificities on RNA molecules.
引用
收藏
页码：453 / 456
页数：4
相关论文
共 8 条
  • [1] UNEXPECTED ACTIVITY OF SAPORINS
    BARBIERI, L
    GORINI, P
    VALBONESI, P
    CASTIGLIONI, P
    STIRPE, F
    [J]. NATURE, 1994, 372 (6507) : 624 - 624
  • [2] BARBIERI L, 1992, BIOCHEM J, V286, P1
  • [3] ENDO Y, 1987, J BIOL CHEM, V262, P5908
  • [4] TOXICITY AND ACTIVITY OF PURIFIED TRICHOSANTHIN
    FERRARI, P
    TRABAUD, MA
    ROMMAIN, M
    MANDINE, E
    ZALISZ, R
    DESGRANGES, C
    SMETS, P
    [J]. AIDS, 1991, 5 (07) : 865 - 870
  • [5] TRICHOSANTHIN, A POTENT HIV-1 INHIBITOR, CAN CLEAVE SUPERCOILED DNA INVITRO
    LI, MX
    YEUNG, HW
    PAN, LP
    CHAN, SI
    [J]. NUCLEIC ACIDS RESEARCH, 1991, 19 (22) : 6309 - 6312
  • [6] GLQ223 - AN INHIBITOR OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION IN ACUTELY AND CHRONICALLY INFECTED-CELLS OF LYMPHOCYTE AND MONONUCLEAR PHAGOCYTE LINEAGE
    MCGRATH, MS
    HWANG, KM
    CALDWELL, SE
    GASTON, I
    LUK, KC
    WU, P
    NG, VL
    CROWE, S
    DANIELS, J
    MARSH, J
    DEINHART, T
    LEKAS, PV
    VENNARI, JC
    YEUNG, HW
    LIFSON, JD
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (08) : 2844 - 2848
  • [7] RIBONUCLEASE-ACTIVITY ASSOCIATED WITH THE 60S RIBOSOME-INACTIVATING PROTEINS RICIN-A, PHYTOLACCIN AND SHIGA TOXIN
    OBRIG, TG
    MORAN, TP
    COLINAS, RJ
    [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1985, 130 (02) : 879 - 884
  • [8] 1974, AZTA ZOOLOGICA SINIC, V22, P126
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