A simple, convenient and effective method for the synthesis of dibenz(B,F) 1,4-oxazepines(CR); A new generation, riot control agent and its analogues

被引：0

作者：

Gutch, P. K. ^{[1
]}

Acharya, J. ^{[1
]}

机构：

[1] Def Res & Dev Estab, Synthet Chem Div, Gwalior 474006, India

来源：

HETEROCYCLIC COMMUNICATIONS | 2007年 / 13卷 / 06期

关键词：

dibenz(b,f) 1,4-oxazepine; CR; o-aminophenol; o-chlorobenzaldehyde; Schiff s base;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthetic route has been developed for the synthesis of seven membered heterocyclic ring dibenz (b, f) 1,4-oxazepine (CR) starting with condensation of o-aminophenol and o-chlorobenzaldehyde followed by salt formation and cyclisation in DMSO at 120 degrees C. The method has been extended for the preparation of other substituted dibenzoxazepines.

引用

页码：393 / 396

页数：4

共 3 条

[1] Studies on thermal degradation of riot control agent dibenz[b,f]-1,4-oxazepine (CR)
Suryanarayana, M. V. S.
Nigam, Anil K.
Mazumder, Avik
Gutch, Pranav K.
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2017, 56 (08): : 862 - 871
[2] Synthesis and evaluation of antipsychotic activity of 11-(4-aryl-1-piperazinyl)-dibenz [b, f][1,4] oxazepines and their 8-chloro analogues
Wagh, B. S.
Patil, B. P.
Jain, M. S.
Harak, S. S.
Wagh, S. B.
HETEROCYCLIC COMMUNICATIONS, 2007, 13 (2-3) : 165 - 172
[3] Evaluation of 1-chloroacetophenone (CN) and dibenz(b,f)-1,4 oxazepine (CR) induced respiratory tract sensory irritation following a simple inhalation exposure method in mice
Kumar, P
Sachan, AS
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 1998, 11 (02) : 171 - 178

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