Oral combined hormonal contraception containing nomegestrol acetate and 17β-oestradiol - the statement of Polish Gynecological Society Experts Group

被引:0
|
作者
Debski, Romuald
Kotarski, Jan
Paszkowski, Tomasz
Pawelczyk, Leszek
Poreba, Ryszard
Skrzypulec-Plinta, Violetta
Tomaszewski, Jacek
机构
关键词
oral hormonal contraception; nomegestrol acetate; 17; beta-oestradiol;
D O I
暂无
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Nomegestrol acetate (NOMAD) combined with E-2 (Zoely (R)) is a monophasic oral contraceptive (00) which safety and efficacy was confirmed in a number of level I evidence clinical trials. Zoely (R) is highly effective OC, especially in overweight and obese patients, with good cycle control, safe and well tolerated. NOMAC/E2 combination causes no or minimal weight gain and is characterized by minimal influence on bone mineral density or blood pressure and presence of acne. Moreover lipids profile, carbohydrates metabolism, haemostasis and endocrine glands functioning were not affected. High tolerance and acceptance of NOMAC/E2 combination by women, low adverse event profile, fast recovery of ovarian activity and ovulation is a reasonable treatment tool in everyday practice.
引用
收藏
页码:316 / 318
页数:3
相关论文
共 13 条
  • [1] Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol
    Duijkers, Ingrid J. M.
    Klipping, Christine
    Grob, Paul
    Korver, Tjeerd
    EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2010, 15 (05): : 314 - 325
  • [2] Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol in comparison to one containing levonorgestrel and ethinylestradiol on markers of endocrine function
    Agren, Ulla M.
    Anttila, Marjatta
    Maenpaa-Liukko, Kristiina
    Rantala, Maija-Liisa
    Rautiainen, Hilkka
    Sommer, Werner F.
    Mommers, Ellen
    EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2011, 16 (06): : 458 - 467
  • [3] Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol compared with one containing levonorgestrel and ethinylestradiol on haemostasis, lipids and carbohydrate metabolism
    Agren, Ulla M.
    Anttila, Marjatta
    Maenpaa-Liukko, Kristiina
    Rantala, Maija-Liisa
    Rautiainen, Hilkka
    Sommer, Werner F.
    Mommers, Ellen
    EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2011, 16 (06): : 444 - 457
  • [4] Treatment continuation and satisfaction in women using combined oral contraception with nomegestrol acetate and oestradiol: a multicentre, prospective cohort study (BOLERO)
    Cagnacci, Angelo
    Bastianelli, Carlo
    Neri, Manuela
    Cianci, Antonio
    Benedetto, Chiara
    Calanni, Luana
    Vignali, Michele
    De Leo, Vincenzo
    Cicinelli, Ettore
    Borrelli, Giuseppe
    Volpe, Annibale
    Alio, Luigi
    Bucciantini, Sandra
    Caruso, Salvatore
    Cetin, Irene
    De Seta, Francesco
    Di Carlo, Costantino
    Driul, Lorenza
    Farris, Manuela
    Ferrero, Simone
    Fruzzetti, Franca
    Maiorana, Antonio
    Marchesoni, Diego
    Nappi, Carmine
    Nappi, Rossella
    Neri, Manuela
    Pampaloni, Francesca
    Paoletti, Anna Maria
    Petraglia, Felice
    Scagliola, Pasquale
    Venturini, Pierluigi
    EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2018, 23 (06): : 393 - 399
  • [5] Efficacy and tolerability of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol in a 24/4 regimen, in comparison to an oral contraceptive containing ethinylestradiol and drospirenone in a 21/7 regimen
    Mansour, Diana
    Verhoeven, Carole
    Sommer, Werner
    Weisberg, Edith
    Taneepanichskul, Surasak
    Melis, Gian Benedetto
    Sundstrom-Poromaa, Inger
    Korver, Tjeerd
    EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE, 2011, 16 (06): : 430 - 443
  • [6] The effectiveness of quick starting oral contraception containing nomegestrol acetate and 17-β estradiol on ovulation inhibition: A randomized controlled trial
    Preeyaporn Jirakittidul
    Surasak Angsuwathana
    Manee Rattanachaiyanont
    Thunyada Thiampong
    Chanon Neungton
    Benjaphorn Chotrungrote
    Scientific Reports, 10
  • [7] The effectiveness of quick starting oral contraception containing nomegestrol acetate and 17-β estradiol on ovulation inhibition: A randomized controlled trial
    Jirakittidul, Preeyaporn
    Angsuwathana, Surasak
    Rattanachaiyanont, Manee
    Thiampong, Thunyada
    Neungton, Chanon
    Chotrungrote, Benjaphorn
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [8] Position Statement by Experts of the Polish Menopause and Andropause Society on menopausal hormone therapy with an oral combination drug containing oestradiol 1 mg and progesterone 100 mg
    Binkowska, Malgorzata
    Jakiel, Grzegorz
    Paszkowski, Tomasz
    Skrzypulec-Plinta, Violetta
    Zgliczynski, Wojciech
    MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY, 2021, 20 (03): : 113 - 115
  • [9] Effects on bone mineral density of a monophasic combined oral contraceptive containing nomegestrol acetate/17β-estradiol in comparison to levonorgestrel/ethinylestradiol
    Sordal, Terje
    Grob, Paul
    Verhoeven, Carole
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2012, 91 (11) : 1279 - 1285