Effect of verbascoside on decreasing concentration of oxygen free radicals and lipid peroxidation in skeletal muscle

被引：0
|
作者：
Li, JX
Xin, D
Li, H
Lu, JF
Tong, CWC
Gao, JN
Chan, KM
机构：
[1] Chinese Univ Hong Kong, Dept Orthoped & Traumatol, Hong Kong, Peoples R China
[2] Tianjin Res Inst Sports Med, Tianjin 300381, Peoples R China
[3] Beijing Med Univ, Natl Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
来源：
ACTA PHARMACOLOGICA SINICA | 1999年 / 20卷 / 02期
关键词：
free radicals; electron spin resonance spectroscopy; lipid peroxidation; exercise; skeletal muscle; malondialdehyde;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
AIM: To detect the effects of verbascoside on decreasing the concentration of oxygen free radicals (OFR) and lipid peroxidation in skeletal muscle resulting from exhaustive exercise. METHODS: Electron spin resonance (ESR) technique and thiobarbituric acid reaction (TBAR) method were used to detect the concentration of OFR in intact gastrocnemius muscle and the contents of milondialdehyde (MDA) in muscle homogenate. RESULTS: Verbascoside decreased the concentration of OFR (P < 0.05) and the level of lipid peroxidation (P < 0.05) in muscle caused by exercise. CONCLUSION: Verbascoside has the effects of reducing oxidative stress in muscle caused by exhaustive exercise by decreasing the concentration of free radicals and the level of lipid peroxidation.
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页码：126 / 130
页数：5
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