Molecular motor efficiency is maximized in the presence of both power-stroke and rectification through feedback

被引:23
|
作者
Schmitt, R. K. [1 ]
Parrondo, J. M. R. [2 ,3 ]
Linke, H. [1 ]
Johansson, J. [1 ]
机构
[1] Lund Univ, Solid State Phys & Nanometer Struct Consortium Nm, SE-22100 Lund, Sweden
[2] Univ Complutense Madrid, Dept Fis Atom Mol & Nucl, E-28040 Madrid, Spain
[3] Univ Complutense Madrid, GISC, E-28040 Madrid, Spain
来源
NEW JOURNAL OF PHYSICS | 2015年 / 17卷
基金
瑞典研究理事会;
关键词
molecular motor; Brownian ratchet; power-stroke; rectification of fluctuations; efficiency; Shannon entropy; Brownian recitifier; SINGLE KINESIN MOLECULE; FORCE; THERMODYNAMICS; INFORMATION; KINETICS; PROTEIN; STEPS; MODEL; LOAD;
D O I
10.1088/1367-2630/17/6/065011
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
We present a model for a feedback-controlled ratchet consisting of a Brownian particle and a moving, finite barrier that is shifted by an external agent depending on the position of the particle. By modifying the value of a single parameter of the feedback protocol, the model can act either as a pure rectifier, a power-stroke (PS) motor, or a combination of both. Interestingly, in certain situations the motor reaches a maximum efficiency for an intermediate value of that parameter, i.e., for a combination of the information ratchet and the PS mechanisms. We relate our results to the biological motors kinesin, myosin II, and myosin V, finding that these motors operate in a regime of length scales and forces where the efficiency is maximized for a combination of rectification and PS mechanisms.
引用
收藏
页数:10
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