Synthesis of new 5-substituted hydantoins from 2-alkoxy-1-cyano-1-trimethylsiloxypropenes

被引：5
|
作者：
Keiko, N. A. [1 ]
Kuznetsova, T. A. [1 ]
Vchislo, N. V. [1 ]
Chuvashev, Yu. A. [1 ]
Larina, L. I. [1 ]
Voronkov, M. G. [1 ]
机构：
[1] Russian Acad Sci, Siberian Div, Favorskii Irkutsk Inst Chem, Irkutsk 664033, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2007年 / 77卷 / 12期
关键词：
D O I：
10.1134/S1070363207120122
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthetic procedures for preparing previously unknown 5-(1'-alkoxyethylidene)hydantoins from 2-alkoxy-1-cyano-1-trimethylsiloxy-1-(or -2-)propenes by one-pot successive reactions with ethanol and (NH4)(2)CO3 are developed. Some intermediates, reaction mechanism, and parameters determining the optimal yields are considered. Acid hydrolysis of ethylidenehydantoins occurs at the vinyloxy group and gives 5-acetyl-hydantoin in 64% yield.
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收藏
页码：2145 / 2149
页数：5
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