RiboSketch: versatile visualization of multi-stranded RNA and DNA secondary structure

被引:15
|
作者
Lu, Jacob S. [1 ]
Bindewald, Eckart [2 ]
Kasprzak, Wojciech K. [2 ]
Shapiro, Bruce A. [1 ]
机构
[1] NCI, RNA Biol Lab, Frederick, MD 21702 USA
[2] NCI, Basic Sci Program, RNA Biol Lab, Frederick Natl Lab Canc Res, Frederick, MD 21702 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1093/bioinformatics/bty468
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Creating clear, visually pleasing 2D depictions of RNA and DNA strands and their interactions is important to facilitate and communicate insights related to nucleic acid structure. Here we present RiboSketch, a secondary structure image production application that enables the visualization of multistranded structures via layout algorithms, comprehensive editing capabilities, and a multitude of simulation modes. These interactive features allow RiboSketch to create publication quality diagrams for structures with a wide range of composition, size and complexity. The program may be run in any web browser without the need for installation, or as a standalone Java application.
引用
收藏
页码:4297 / 4299
页数:3
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