Statins reduce amyloid-induced inflammation

被引:0
|
作者
Hrastar, LM
机构
来源
SCIENTIST | 2005年 / 19卷 / 02期
关键词
D O I
暂无
中图分类号
G25 [图书馆学、图书馆事业]; G35 [情报学、情报工作];
学科分类号
1205 ; 120501 ;
摘要
Statin drugs appear to reduce inflammation associated with Alzheimer disease in a cholesterol independent manner, say researchers from Case Western Reserve University, Cleveland. Gary Landreth, professor of neurosciences and neurology, and colleague Andrew Cordle found that statins hinder microglial inflammation by decreasing isoprenyl intermediates in the cholesterol pathway.
引用
收藏
页码:22 / 22
页数:1
相关论文
共 50 条
  • [1] Locus ceruleus regulates β-amyloid-induced cortical inflammation
    Feinstein, DL
    Galea, E
    Gavrilyuk, V
    Dumetiscu, L
    Heneka, MT
    ANNALS OF NEUROLOGY, 2001, 50 (03) : S16 - S16
  • [2] Penetratin and Mannose-Functionalized Cannabidiol Lipid Nanoparticles Encapsulating the BDNF Gene Reduce Amyloid-Induced Inflammation
    Chaulagain, Bivek
    Singh, Jagdish
    MOLECULAR PHARMACEUTICS, 2024,
  • [3] REDUCED β-AMYLOID-INDUCED NEURO-INFLAMMATION IN GMF-DEFICIENT MICE
    Zaheer, A.
    Zaheer, S.
    Thangavel, R.
    Sahu, S. K.
    Yang, B.
    JOURNAL OF NEUROCHEMISTRY, 2009, 108 : 151 - 151
  • [4] Tau is essential to β-amyloid-induced neurotoxicity
    Rapoport, M
    Dawson, HN
    Binder, LI
    Vitek, MP
    Ferreira, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (09) : 6364 - 6369
  • [5] Amyloid-induced neurofibrillary tangle formation
    Götz, J
    Chen, F
    Ferrari, A
    Kurosinski, P
    Schild, A
    Nitsch, RM
    van Dorpe, J
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S567 - S567
  • [6] Noradrenergic depletion potentiates β-amyloid-induced cortical inflammation:: implications for Alzheimer's disease
    Heneka, MT
    Galea, E
    Gavriluyk, V
    Dumitrescu-Ozimek, L
    Daeschner, J
    O'Banion, MK
    Weinberg, G
    Klockgether, T
    Feinstein, DL
    JOURNAL OF NEUROSCIENCE, 2002, 22 (07): : 2434 - 2442
  • [7] Natural lipopeptide surfactin inhibits insulin aggregation and prevents amyloid-induced cytotoxicity and inflammation
    Panda, Chinmaya
    Dumka, Shaurya
    Kumar, Sachin
    Gupta, Sharad
    Pandey, Lalit M.
    JOURNAL OF MOLECULAR LIQUIDS, 2024, 404
  • [8] Endocannabinoid regulation of amyloid-induced neuroinflammation
    Vazquez, Carmen
    Tolon, Rosa M.
    Teresa Grande, M.
    Caraza, Marina
    Moreno, Marta
    Koester, Erin C.
    Villaescusa, Borja
    Ruiz-Valdepenas, Lourdes
    Javier Fernandez-Sanchez, Francisco
    Cravatt, Benjamin F.
    Hillard, Cecilia J.
    Romero, Julian
    NEUROBIOLOGY OF AGING, 2015, 36 (11) : 3008 - 3019
  • [9] The effect of cannabinoid treatment on amyloid-induced inflammation via the hemichannel, PANX1
    Fagan, S. G.
    Campbell, V. A.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2014, 183 : S83 - S84
  • [10] Crystalline aloe-emodin reduce β-amyloid-induced toxicity in Caenorhabditis elegans with visualization of ingestion
    Wang, Ruo-Yi
    Liang, Guiling
    Tan, Wen-Wu
    Yang, Tao
    JOURNAL OF MOLECULAR STRUCTURE, 2024, 1311