Room-Temperature Nickel-Catalysed Suzuki-Miyaura Reactions of Aryl Sulfonates/Halides with Arylboronic Acids

Room-temperature Suzuki-Miyaura aryl-aryl cross-coupling reactions have been achieved in high yields by using an easily accessible, air-stable Ni-II-(sigma-aryl) complex as precatalyst without either the pretreatment of organometallic reagents or the presence of external reductants. The Ni-II complex, in conjunction with monophosphane ligands such as PCy3 center dot HBF4 or PPh3, allowed the efficient cross-coupling of aryl sulfonates (OTs, OMs) and/or halides (Cl, Br, I) with arylboronic acids at room temperature in toluene/water in the presence of K2CO3 as base.