Diabetes Mellitus and Risk of Hepatocellular Carcinoma

被引：39
|
作者：
Li, Xu [1 ]
Wang, Xiaocong [2 ]
Gao, Pujun [1 ]
机构：
[1] Jilin Univ, Hosp 1, Dept Hepatol, 71 Xinmin St, Changchun 130021, Jilin, Peoples R China
[2] Jilin Univ, Hosp 1, Dept Echocardiog, 71 Xinmin St, Changchun 130021, Jilin, Peoples R China
来源：
BIOMED RESEARCH INTERNATIONAL | 2017年 / 2017卷
关键词：
HEPATITIS-C VIRUS; FATTY LIVER-DISEASE; ACTIVATED RECEPTOR-GAMMA; CANCER-RISK; INSULIN-RESISTANCE; NONALCOHOLIC STEATOHEPATITIS; B-VIRUS; ALCOHOLIC LIVER; EPIDEMIOLOGIC EVIDENCE; ANTIDIABETIC THERAPY;
D O I：
10.1155/2017/5202684
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The occurrence of hepatocellular carcinoma (HCC) is two to three times higher in patients with diabetes mellitus (DM), the prevalence of which is increasing sharply worldwide. The purpose of this review was to describe clinical links between DM and HCC and potential biological mechanisms that may account for this association. We evaluated the role of potential pathways that could account for the development of HCC with different etiologies in the presence of DM. In addition, we also briefly discuss the potential effect of other factors such as type and dosage of antidiabetic medicines and duration of DM on HCC risk.
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页数：10
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